Drug Interaction Report

Talk to your doctor before using omega-3 polyunsaturated fatty acids together with drotrecogin alfa. Fish oil and other products containing omega-3 fatty acids may rarely increase the risk of bleeding when combined with other medications that can also cause bleeding such as drotrecogin alfa. You should seek immediate medical attention if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.