Drug Interaction Report

Using donepezil together with atropine may decrease the benefits of donepezil in the treatment of dementia. Donepezil may also counteract the benefit of atropine. Atropine should generally be avoided in patients with Alzheimer's disease or other cognitive problems. Atropine may also adversely affect elderly patients by producing symptoms ranging from mild thinking impairment to delirium. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.

Information for this minor interaction is available on the professional version.

Ask your doctor before using atropine together with ethanol (alcohol). Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking atropine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.