Drug Interaction Report

Ask your doctor before using cidofovir together with brincidofovir. The active medication in brincidofovir is the same as cidofovir, so they are normally not used together. Doing so may increase side effects such as diarrhea, liver problems, decreased levels of white blood cells, and kidney damage. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food may decrease the blood levels of brincidofovir. It is recommended that you take brincidofovir on an empty stomach, meaning no food should be eaten for at least two hours before or after taking brincidofovir. If necessary, you may take the oral tablets (but not the suspension formulation) with a low-fat meal. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

The recommended maximum number of medicines in the 'acyclovir-like antivirals' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'acyclovir-like antivirals' category:

• brincidofovir
• cidofovir

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.