Drug Interaction Report

If you are currently taking or have taken etrasimod within the past month, you should talk to your doctor before receiving SARS-CoV-2 (COVID-19) ChAdOx1 vaccine, recombinant. Depending on the length of time you have been on etrasimod, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of etrasimod therapy. If you have recently been vaccinated with SARS-CoV-2 (COVID-19) ChAdOx1 vaccine, recombinant, your doctor may choose to postpone treatment with etrasimod for 1 month. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Grapefruit juice may increase the blood levels of etrasimod. You should avoid grapefruit, grapefruit juice, or any supplements that contain grapefruit extract during treatment with etrasimod unless directed otherwise by your doctor. Talk to your doctor if you have any questions or concerns. Contact your doctor if your condition changes or you experience increased side effects, such as fever, high temperature or flu-like symptoms, severe headache, confusion, seizures, dizziness, tiredness, lightheadedness, chest pain, shortness of breath, or irregular or abnormal heartbeat, blurriness or shadows in the center of your vision, and nausea, vomiting, abdominal pain, anorexia, or jaundice and/or dark urine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.