Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- bleomycin
- indium pentetreotide in-111
Interactions between your drugs
bleomycin indium pentetreotide In-111
Applies to: bleomycin, indium pentetreotide in-111
MONITOR: Indium In-111 pentetreotide may accumulate in the lungs when given concomitantly with bleomycin.
MANAGEMENT: Clinicians should be aware of possible diagnostic interference in patients who are undergoing bleomycin treatment. To help reduce the radiation dose to the lungs and other target organs (e.g., thyroid, kidneys, bladder), patients should be well hydrated prior to the administration of indium In-111 pentetreotide. They should increase fluid intake and void frequently for one day after the scintigraphy. In addition, it is recommended that patients be given a mild laxative (e.g., bisacodyl or lactulose) before and after administration of indium In-111 pentetreotide.
References (1)
- (2022) "Product Information. Octreoscan (indium pentetreotide In-111)." Mallinckrodt Medical Inc
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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