Drug Interaction Report

Using burosumab together with cinacalcet may cause a condition known as hypocalcemia, or low blood calcium. Symptoms of hypocalcemia include numbness or tingling around your mouth, muscle spasms, convulsions, mental changes (irritability, depression, psychosis), increased pressure on the brain, and irregular heartbeat. Let your doctor know if you experience these or other unusual symptoms. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food can enhance the levels of cinacalcet in your body. Cinacalcet should be taken just after eating food. Do not take it on an empty stomach. This will make it easier for your body to absorb the medication. Do not crush, chew, or break the tablets. Swallow them whole.