Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- coagulation factor x
- Xarelto (rivaroxaban)
Interactions between your drugs
rivaroxaban coagulation factor X
Applies to: Xarelto (rivaroxaban), coagulation factor x
GENERALLY AVOID: Based on their mechanisms of action, the pharmacologic activity of coagulation factor X is likely to be counteracted by direct and indirect factor Xa inhibitors. In vivo, factor X is converted from its inactive form to the active form, factor Xa, by the cleavage of a 52-residue peptide from the heavy chain.
MANAGEMENT: Concomitant use of coagulation factor X with direct and indirect factor Xa inhibitors should be avoided.
References (1)
- (2022) "Product Information. Coagadex (coagulation factor X)." Bio Products Laboratory
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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