Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- Prograf (tacrolimus)
- sparfloxacin
Interactions between your drugs
tacrolimus sparfloxacin
Applies to: Prograf (tacrolimus), sparfloxacin
Sparfloxacin is no longer commercially available in the US. Do not take sparfloxacin with any other medication.
Drug and food/lifestyle interactions
tacrolimus food/lifestyle
Applies to: Prograf (tacrolimus)
Tacrolimus should be taken on a consistent schedule before or after you eat at the same times each day. Grapefruit and grapefruit juice may increase the amount of tacrolimus in your body. This can lead to potentially dangerous side effects and should be avoided. If you are already consuming grapefruit products, do not increase or decrease the amount of these products in your diet without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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