Drug Interaction Report
5 potential interactions and/or warnings found for the following 2 drugs:
- mifepristone
- Nuedexta (dextromethorphan / quinidine)
Interactions between your drugs
quiNIDine dextromethorphan
Applies to: Nuedexta (dextromethorphan / quinidine), Nuedexta (dextromethorphan / quinidine)
Using dextromethorphan together with quiNIDine may increase the effects of dextromethorphan. Contact your doctor if you experience difficulty breathing, dizziness, drowsiness, anxiety, restless feeling, nervousness, confusion, or diarrhea. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
quiNIDine miFEPRIStone
Applies to: Nuedexta (dextromethorphan / quinidine), mifepristone
Talk to your doctor before using quiNIDine together with miFEPRIStone. Combining these medications may significantly increase the blood levels of quiNIDine, which may increase the risk and/or severity of side effects. Your doctor may be able to prescribe alternatives that do not interact, or you may need to briefly stop using quiNIDine while you are being treated with miFEPRIStone. In addition, because miFEPRIStone is cleared slowly from the body, the interaction may occur even after you have stopped taking it for a while. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food/lifestyle interactions
quiNIDine food/lifestyle
Applies to: Nuedexta (dextromethorphan / quinidine)
Do not consume grapefruit or grapefruit juice during treatment with quiNIDine unless specifically directed otherwise by your doctor. Grapefruit and grapefruit juice can interact with quiNIDine and increase the levels of quiNIDine in your body. If you are already consuming grapefruit products, do not increase or decrease the amount of these products in your diet without first talking to your doctor.
dextromethorphan food/lifestyle
Applies to: Nuedexta (dextromethorphan / quinidine)
Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with dextromethorphan. Do not use more than the recommended dose of dextromethorphan, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
miFEPRIStone food/lifestyle
Applies to: mifepristone
Food increases the blood levels of this medication. If you are only receiving one or two doses, you may take it without regard to meals. However, if you are receiving the medication for long-term treatment, you should take it with food at the same time everyday to maintain consistent blood levels and effects. Avoid consuming grapefruit or grapefruit juice during treatment, as it may increase blood levels of the medication to undesirable levels and increase the risk of side effects, including headache, dizziness, fatigue, nausea, vomiting, cramping, diarrhea, hypokalemia (low blood potassium), fluid retention, swelling, and high blood pressure. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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