Drug Interaction Report

If you are currently being treated with vardenafil, let your doctor know before you receive amifostine. Combining these medications may have additive effects in lowering your blood pressure. Depending on your condition, your doctor may want you to discontinue vardenafil for 24 hours before you receive treatment with amifostine, and your blood pressure will need to be monitored closely during and after the treatment. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. Contact your doctor if you develop these symptoms and they do not go away after a few hours, or they become troublesome. You should avoid rising abruptly from a sitting or lying position until you know how these medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Grapefruit juice may increase the blood levels of certain medications such as vardenafil. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with vardenafil. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.