Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- lepirudin
- Zontivity (vorapaxar)
Interactions between your drugs
lepirudin vorapaxar
Applies to: lepirudin, Zontivity (vorapaxar)
GENERALLY AVOID: Coadministration of vorapaxar with other agents that affect hemostasis such as anticoagulants may increase the risk of bleeding complications, including intracranial hemorrhage and fatal bleeding.
MANAGEMENT: Concomitant use of vorapaxar with warfarin or other anticoagulants should generally be avoided.
References (1)
- (2014) "Product Information. Zontivity (vorapaxar)." Merck & Co., Inc
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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