Tecovirimat and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with tecovirimat.
Tecovirimat Food/Lifestyle
Moderate Food Interaction
ADJUST DOSING INTERVAL: Food may increase the extent of tecovirimat absorption following oral administration. When the recommended oral dose of tecovirimat (600 mg every 12 hours) was administered with a meal (approximately 600 calories and 25 g of fat) in healthy adults weighing less than 120 kg, tecovirimat absorption increased by 39% relative to fasting.
MANAGEMENT: Oral tecovirimat should be taken within 30 minutes after a full meal containing moderate or high fat (approximately 600 calories and 25 g of fat) with 6 to 8 ounces of water.
References (1)
- "Product Information. Tpoxx (tecovirimat)." SIGA Technologies, Inc.
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Tecovirimat drug interactions
There are 296 drug interactions with tecovirimat.
Tecovirimat disease interactions
There is 1 disease interaction with tecovirimat which include:
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- Drug class: miscellaneous antivirals
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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