Maralixibat and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with maralixibat.
Multivitamins With Minerals Maralixibat
Moderate Drug Interaction
MONITOR: Maralixibat may affect the absorption of fat-soluble vitamins (FSV) including A, D, E, and K. In a clinical study, emergent FSV deficiency was reported in 10% of patients during 48 weeks of treatment. In addition, it should be noted that patients with Alagille syndrome (ALGS) can have FSV deficiency at baseline.
MANAGEMENT: Clinical and laboratory monitoring of serum FSV levels is recommended at baseline and during treatment with maralixibat. If FSV deficiency is diagnosed, supplementation with FSV should be initiated. If FSV deficiency persists or worsens despite adequate FSV supplementation, discontinuation of maralixibat should be considered.
References (1)
- (2021) "Product Information. Livmarli (maralixibat)." Mirum Pharmaceuticals, Inc.
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Maralixibat drug interactions
There are 64 drug interactions with maralixibat.
Maralixibat disease interactions
There are 2 disease interactions with maralixibat which include:
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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