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Afinitor (everolimus) and Alcohol / Food Interactions

There are 2 alcohol/food/lifestyle interactions with Afinitor (everolimus) which include:

Moderate

everolimus ↔ food

Moderate Food Interaction

Grapefruit juice can increase the blood levels and effects of everolimus. You should not drink grapefruit juice or eat grapefruits during your treatment with everolimus. Orange juice is not expected to interact.

Switch to professional interaction data

Moderate

High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)

Moderate Potential Hazard, Moderate plausibility

everolimus - cholesterol

Elevations in cholesterol and triglyceride levels have been reported in patients taking everolimus. Monitoring of fasting lipid profile is recommended prior to the start of everolimus therapy and periodically thereafter. Clinicians should achieve control of lipid levels before initiating therapy with this agent.

Afinitor (everolimus) drug Interactions

There are 329 drug interactions with Afinitor (everolimus)

Afinitor (everolimus) disease Interactions

There are 7 disease interactions with Afinitor (everolimus) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.

Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.

Do not stop taking any medications without consulting your healthcare provider.

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