Acetaminophen/chlorpheniramine/phenylephrine Interactions
There are 572 drugs known to interact with acetaminophen/chlorpheniramine/phenylephrine, along with 11 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 43 are major, 514 are moderate, and 15 are minor.
- View all 572 medications that may interact with acetaminophen/chlorpheniramine/phenylephrine
- View acetaminophen/chlorpheniramine/phenylephrine alcohol/food interactions (1)
- View acetaminophen/chlorpheniramine/phenylephrine disease interactions (11)
Most frequently checked interactions
View interaction reports for acetaminophen / chlorpheniramine / phenylephrine and the medicines listed below.
- 5-HTP (5-hydroxytryptophan)
- Acidophilus (lactobacillus acidophilus)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Aleve (naproxen)
- Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate)
- Alka-Seltzer Plus Maximum Strength Day & Night Cold & Flu Liquid Gels (Night Formula) (acetaminophen / dextromethorphan / doxylamine / phenylephrine)
- Alka-Seltzer Plus Night Cold Formula Effervescent Tablets (aspirin / dextromethorphan / doxylamine / phenylephrine)
- Allegra (fexofenadine)
- Ambien (zolpidem)
- Augmentin (amoxicillin / clavulanate)
- Azithromycin Dose Pack (azithromycin)
- Benadryl (diphenhydramine)
- Celebrex (celecoxib)
- Cymbalta (duloxetine)
- Excedrin PM Headache (acetaminophen / aspirin / diphenhydramine)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Lexapro (escitalopram)
- MethylPREDNISolone Dose Pack (methylprednisolone)
- Metoprolol Tartrate (metoprolol)
- Mucinex DM (dextromethorphan / guaifenesin)
- Nexium (esomeprazole)
- Proventil HFA (albuterol)
- Vicks NyQuil Cold & Flu Nighttime Relief (acetaminophen / dextromethorphan / doxylamine)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Wellbutrin XL (bupropion)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Acetaminophen/chlorpheniramine/phenylephrine alcohol/food interactions
There is 1 alcohol/food interaction with acetaminophen / chlorpheniramine / phenylephrine.
Acetaminophen/chlorpheniramine/phenylephrine disease interactions
There are 11 disease interactions with acetaminophen / chlorpheniramine / phenylephrine which include:
- alcoholism
- liver disease
- cardiovascular disease
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- BPH
- diabetes
- glaucoma
Report options
More about acetaminophen / chlorpheniramine / phenylephrine
- acetaminophen/chlorpheniramine/phenylephrine consumer information
- Compare alternatives
- Reviews (22)
- Drug images
- Side effects
- Dosage information
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
