Skip to Content
Learn about Mavyret, a treatment for Hepatitis C

Drug interactions between simeprevir and Sovaldi

Results for the following 2 drugs:
simeprevir
Sovaldi (sofosbuvir)

Interactions between your drugs

There were no interactions found in our database between simeprevir and Sovaldi - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

simeprevir

A total of 159 drugs (494 brand and generic names) are known to interact with simeprevir.

Sovaldi

A total of 31 drugs (119 brand and generic names) are known to interact with Sovaldi.

Drug and food interactions

Moderate

simeprevir food

Applies to: simeprevir

Food significantly increases the absorption of simeprevir. You should take each dose of simeprevir with food. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication.

Switch to professional interaction data

Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide