Sovaldi Interactions
There are 85 drugs known to interact with Sovaldi (sofosbuvir), along with 3 disease interactions. Of the total drug interactions, 17 are major, 67 are moderate, and 1 is minor.
- View all 85 medications that may interact with Sovaldi
- View Sovaldi disease interactions (3)
Most frequently checked interactions
View interaction reports for Sovaldi (sofosbuvir) and the medicines listed below.
- amlodipine
- Benadryl (diphenhydramine)
- bupropion
- clonazepam
- cyclobenzaprine
- Daklinza (daclatasvir)
- diclofenac
- gabapentin
- Harvoni (ledipasvir / sofosbuvir)
- hydrochlorothiazide
- lactulose
- levothyroxine
- lisinopril
- lorazepam
- metformin
- Olysio (simeprevir)
- omeprazole
- ondansetron
- oxycodone
- Pegasys (peginterferon alfa-2a)
- prednisone
- Protonix (pantoprazole)
- ranitidine
- RibaPak (ribavirin)
- Ribasphere (ribavirin)
- ribavirin
- tramadol
- trazodone
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
Sovaldi disease interactions
There are 3 disease interactions with Sovaldi (sofosbuvir) which include:
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More about Sovaldi (sofosbuvir)
- Sovaldi consumer information
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- Reviews (47)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- FDA approval history
- Drug class: miscellaneous antivirals
- Breastfeeding
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
