Sovaldi (sofosbuvir) Drug Interactions
A total of 28 drugs (113 brand and generic names) are known to interact with Sovaldi (sofosbuvir).
- 24 major drug interactions (103 brand and generic names)
- 3 moderate drug interactions (6 brand and generic names)
- 1 minor drug interactions (4 brand and generic names)
Check for interactions with Sovaldi (sofosbuvir)
Common medications checked in combination with Sovaldi (sofosbuvir)
- amlodipine
- clonazepam
- cyclobenzaprine
- Daklinza (daclatasvir)
- gabapentin
- Harvoni (ledipasvir / sofosbuvir)
- hydrochlorothiazide
- levothyroxine
- metformin
- Olysio (simeprevir)
- omeprazole
- Pegasys (peginterferon alfa-2a)
- prednisone
- Protonix (pantoprazole)
- RibaPak (ribavirin)
- Ribasphere (ribavirin)
- ribavirin
- tramadol
- trazodone
- Vitamin D3 (cholecalciferol)
See also...
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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