Jakafi Drug Interactions
Currently displaying a list of 510 drugs known to interact with Jakafi (ruxolitinib).
- 137 major drug interactions
- 312 moderate drug interactions
- 61 minor drug interactions
Medications known to interact with Jakafi
Note: Showing generic names only.
A
- abametapir topical
- abrocitinib
- acalabrutinib
- adagrasib
- adalimumab
- adenovirus vaccine
- aldesleukin
- alefacept
- alemtuzumab
- allogeneic processed thymus tissue
- aminoglutethimide
- amiodarone
- amobarbital
- amprenavir
- anakinra
- anthrax vaccine adsorbed
- apalutamide
- apixaban
- aprepitant
- ardeparin
- armodafinil
- asciminib
- atazanavir
- atezolizumab
- avacopan
- avapritinib
- avelumab
- azathioprine
B
- baricitinib
- bcg
- bcg vaccine
- belzutifan
- bendamustine
- berotralstat
- betrixaban
- bexarotene
- bicalutamide
- bifidobacterium infantis
- bifidobacterium longum
- bleomycin
- boceprevir
- bosentan
- brewer's yeast
- bromfenac
- bromfenac ophthalmic
- busulfan
- butabarbital
- butalbital
C
- cabazitaxel
- cabozantinib
- canakinumab
- candida albicans extract
- capecitabine
- capivasertib
- capsicum
- carbamazepine
- carboplatin
- carmustine
- cemiplimab
- cenobamate
- ceritinib
- certolizumab
- chamomile
- chikungunya vaccine, live (cvx 317)
- chikungunya vaccine, recombinant (cvx 329)
- chlorambucil
- chloramphenicol
- chloramphenicol ophthalmic
- chloramphenicol otic
- chlorotrianisene
- cholera vaccine
- cholera vaccine, live
- cimetidine
- ciprofloxacin
- cisplatin
- citalopram
- cladribine
- clarithromycin
- clofarabine
- clomiphene
- clomipramine
- clotrimazole
- clozapine
- cobicistat
- coccidioidin skin test
- conivaptan
- conjugated estrogens
- conjugated estrogens topical
- cosibelimab
- COVID-19 mRNA (Moderna) vaccine
- COVID-19 mRNA (Pfizer) vaccine
- crizotinib
- cyclophosphamide
- cyclosporine
- cytarabine
- cytarabine liposomal
D
- dabigatran
- dabrafenib
- dacarbazine
- dactinomycin
- dalteparin
- danaparoid
- danazol
- daridorexant
- darunavir
- dasatinib
- daunorubicin
- daunorubicin liposomal
- decitabine
- deferasirox
- deferiprone
- dehydroepiandrosterone
- delavirdine
- dengue vaccine
- denosumab
- deoxycholic acid
- desvenlafaxine
- deucravacitinib
- dexamethasone
- dexfenfluramine
- diclofenac
- diclofenac ophthalmic
- diclofenac topical
- dienestrol topical
- diethylstilbestrol
- diflunisal
- digoxin
- diltiazem
- dimethyl fumarate
- diroximel fumarate
- docetaxel
- dostarlimab
- doxorubicin
- doxorubicin liposomal
- dronedarone
- drospirenone
- drotrecogin alfa
- duloxetine
- durvalumab
- duvelisib
E
- echinacea
- edoxaban
- efalizumab
- efavirenz
- efbemalenograstim alfa
- eflapegrastim
- elafibranor
- elagolix
- elranatamab
- encorafenib
- enoxaparin
- entrectinib
- enzalutamide
- epirubicin
- erlotinib
- erythromycin
- escitalopram
- esterified estrogens
- estradiol
- estradiol topical
- estramustine
- estrone
- estropipate
- estropipate topical
- etanercept
- ethinyl estradiol
- etodolac
- etonogestrel
- etoposide
- etrasimod
- etravirine
F
- fedratinib
- felbamate
- fenfluramine
- fenoprofen
- fenugreek
- fexinidazole
- filgrastim
- fingolimod
- floxuridine
- fluconazole
- fludarabine
- fluorouracil
- fluoxetine
- flurbiprofen
- flurbiprofen ophthalmic
- fluvoxamine
- fondaparinux
- fosamprenavir
- fosaprepitant
- fosphenytoin
- fostamatinib
G
H
- haemophilus b conjugate (hboc) vaccine
- haemophilus b conjugate (prp-omp) vaccine
- haemophilus b conjugate (prp-t) vaccine
- hemin
- heparin flush
- hepatitis a adult vaccine
- hepatitis a pediatric vaccine
- hepatitis b adult vaccine
- hepatitis b pediatric vaccine
- histoplasmin
- horse chestnut
- human papillomavirus vaccine
- hydroxychloroquine
- hydroxyprogesterone
- hydroxyurea
I
- ibritumomab
- ibrutinib
- ibuprofen
- idarubicin
- idelalisib
- ifosfamide
- imatinib
- indinavir
- indomethacin
- infliximab
- influenza virus vaccine, h1n1, inactivated
- influenza virus vaccine, h1n1, live
- influenza virus vaccine, h5n1
- influenza virus vaccine, inactivated
- influenza virus vaccine, live
- inotersen
- interferon alfa-2a
- interferon alfa-2b
- iodine i 131 tositumomab
- ipilimumab
- iptacopan
- isatuximab
- isavuconazonium
- isoniazid
- itraconazole
- ivosidenib
J
K
L
- lactobacillus acidophilus
- lactobacillus reuteri
- lactobacillus rhamnosus
- lactobacillus rhamnosus gg
- lanreotide
- lapatinib
- larotrectinib
- lazertinib
- lefamulin
- leflunomide
- lenacapavir
- letermovir
- levoketoconazole
- levomilnacipran
- levonorgestrel
- lomitapide
- lomustine
- lonafarnib
- lonapegsomatropin
- loncastuximab tesirine
- lorlatinib
- lurbinectedin
- lyme disease vaccine
M
- mavacamten
- mavorixafor
- measles virus vaccine
- mechlorethamine
- meclofenamate
- medroxyprogesterone
- mefenamic acid
- megestrol
- meloxicam
- melphalan
- melphalan flufenamide
- meningococcal conjugate vaccine
- meningococcal group acwy conjugate-group b vaccine (cvx 316)
- meningococcal group B vaccine
- meningococcal polysaccharide vaccine
- mephobarbital
- mercaptopurine
- methotrexate
- mibefradil
- miconazole
- mifepristone
- milnacipran
- mitapivat
- mitomycin
- mitotane
- mitoxantrone
- mixed respiratory vaccine
- mobocertinib
- modafinil
- monomethyl fumarate
- mumps skin test antigen
- mumps virus vaccine
N
- nabumetone
- nadofaragene firadenovec
- nafcillin
- naproxen
- natalizumab
- naxitamab
- nefazodone
- nelarabine
- nelfinavir
- nepafenac ophthalmic
- nevirapine
- nifedipine
- nilotinib
- niraparib
- nirogacestat
- nivolumab
- norethindrone
- norgestrel
O
- ocrelizumab
- octreotide
- olaparib
- olutasidenib
- omacetaxine
- omaveloxolone
- oritavancin
- osilodrostat
- ospemifene
- oxaliplatin
- oxaprozin
- oxcarbazepine
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- palifermin
- panobinostat
- paroxetine
- pazopanib
- pegfilgrastim
- pembrolizumab
- pemetrexed
- pentobarbital
- pentosan polysulfate sodium
- pentostatin
- pertussis, acellular
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- piroxicam
- pirtobrutinib
- plague vaccine
- pneumococcal 13-valent vaccine
- pneumococcal 15-valent conjugate vaccine
- pneumococcal 20-valent conjugate vaccine
- pneumococcal 21-valent conjugate vaccine
- pneumococcal 23-polyvalent vaccine
- pneumococcal 7-valent vaccine
- poliovirus vaccine, inactivated
- poliovirus vaccine, live, trivalent
- ponatinib
- ponesimod
- posaconazole
- pralsetinib
- prasugrel
- primidone
- progesterone
- progesterone topical
Q
R
- rabies vaccine, human diploid cell
- rabies vaccine, purified chick embryo cell
- radium 223 dichloride
- raloxifene
- ramucirumab
- ranolazine
- regorafenib
- remdesivir
- repotrectinib
- retifanlimab
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rilonacept
- ritlecitinib
- ritonavir
- rivaroxaban
- roflumilast
- ropeginterferon alfa-2b
- rosuvastatin
- rotavirus vaccine
- rsv vaccine pref3, recombinant
- rsv vaccine, mrna
- rsv vaccine, pref a-pref b, recombinant
- rubella virus vaccine
- rucaparib
- rufinamide
- ruxolitinib topical
S
- saccharomyces boulardii lyo
- samarium sm 153 lexidronam
- saquinavir
- sargramostim
- sars-cov-2 (covid-19) ad26 vaccine, recombinant
- sars-cov-2 (covid-19) chadox1 vaccine, recombinant
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
- sars-cov-2 (covid-19) nvx-cov2373 vaccine, recombinant
- sars-cov-2 (covid-19) rs-nanoparticle vaccine, recombinant
- sars-cov-2 mrna (tozinameran 5y-11y) vaccine
- sars-cov-2 mrna (tozinameran 6m-4y) vaccine
- sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine
- sars-cov-2 mrna (tozinameran) vaccine
- sars-cov-2 mrna-1273 (6m-5y) vaccine
- sars-cov-2 mrna-1273 (6y-11y) vaccine
- sars-cov-2 mrna-1273 (booster only) vaccine
- sars-cov-2 nvx-cov2373 vaccine, recomb (cvx 313)
- sars-cov-2 pres dtm (booster only) vaccine, recombinant
- secobarbital
- selpercatinib
- sertraline
- sibutramine
- siponimod
- sipuleucel-T
- skin test antigens, multiple
- smallpox and mpox vaccine
- smallpox vaccine
- sodium phosphate p32
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotorasib
- st. john's wort
- staphage lysate (spl)
- stiripentol
- streptococcus salivarius
- streptozocin
- strontium-89 chloride
- sulfinpyrazone
- sulindac
- suprofen ophthalmic
- suvorexant
- suzetrigine
T
- tafasitamab
- talimogene laherparepvec
- talquetamab
- tamoxifen
- tazemetostat
- tbo-filgrastim
- teclistamab
- tecovirimat
- telaprevir
- telithromycin
- telotristat
- temozolomide
- teriflunomide
- tetanus toxoid
- thalidomide
- thioguanine
- thiotepa
- ticagrelor
- tick-borne encephalitis (inactivated) pediatric vaccine
- tick-borne encephalitis (inactivated) vaccine
- tinzaparin
- tislelizumab
- tofacitinib
- tolmetin
- topotecan
- toremifene
- toripalimab
- tositumomab
- tovorafenib
- trabectedin
- tremelimumab
- treosulfan
- trichophyton skin test
- trofinetide
- troglitazone
- troleandomycin
- tuberculin purified protein derivative
- tucatinib
- typhoid vaccine, inactivated
- typhoid vaccine, live
U
V
- vadadustat
- valganciclovir
- varicella virus vaccine
- vemurafenib
- venlafaxine
- verapamil
- vilazodone
- viloxazine
- vinblastine
- vinorelbine
- voclosporin
- vonoprazan
- vorasidenib
- voriconazole
- vortioxetine
- voxelotor
Y
Z
Jakafi alcohol/food interactions
There are 2 alcohol/food interactions with Jakafi (ruxolitinib).
Jakafi disease interactions
There are 12 disease interactions with Jakafi (ruxolitinib) which include:
- cardiovascular risk
- malignancy
- thrombosis
- lung toxicity
- cytopenia
- hepatic impairment
- Hepatitis B
- infections
- lipid elevations
- PML
- renal impairment
- tuberculosis
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More about Jakafi (ruxolitinib)
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- Reviews (33)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: multikinase inhibitors
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
