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Jakafi (ruxolitinib) Drug Interactions

A total of 416 drugs are known to interact with Jakafi (ruxolitinib).

  • 94 major drug interactions
  • 275 moderate drug interactions
  • 47 minor drug interactions

Show all medications in the database that may interact with Jakafi (ruxolitinib).

Check for interactions

Type in a drug name to check for interactions with Jakafi (ruxolitinib).

Most frequently checked interactions

View interaction reports for Jakafi (ruxolitinib) and the medicines listed below.

  • acyclovir (Zovirax, Sitavig)
  • allopurinol (Zyloprim, Aloprim, Lopurin)
  • amlodipine (Norvasc)
  • aspirin (Aspir 81, Ecotrin, Aspirin Low Strength, Acetylsalicylic Acid, Bayer Aspirin, Aspir-Low, Bufferin, Ascriptin, Arthritis Pain, Aspiritab, Aspergum, Fasprin, Halfprin, Easprin, Ecotrin Adult Low Strength, Empirin, Migralex, Aspi-Cor, St. Joseph 81 mg Chewable Aspirin, Bayer Children's Aspirin, Buffered Aspirin, Durlaza, Ecotrin Maximum Strength, Entercote, Bufferin Extra Strength, Ascriptin Enteric, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Bayer Aspirin Regimen, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Aspirtab, Bufferin Low Dose, Medi-Seltzer, Sloprin, ZORprin, Low Dose ASA, Bayer Aspirin Extra Strength Plus, Buffex, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Therapy Bayer, St. Joseph Aspirin, Stanback Analgesic, Norwich Aspirin, Acuprin 81, Ecpirin, Bayer Women's Aspirin With Calcium, Zero-Order Release, YSP Aspirin, Miniprin, Aspirin Lite Coat, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Aspirin Low Strength (aspirin)
  • atorvastatin (Lipitor)
  • Bactrim (sulfamethoxazole / trimethoprim)
  • clonazepam (Klonopin, Klonopin Wafer)
  • furosemide (Lasix, Diaqua-2, Lo-Aqua)
  • Hydrea (hydroxyurea)
  • hydroxyurea (Hydrea, Droxia, Siklos, Mylocel)
  • hydroxyzine (Vistaril, Atarax, Hyzine, Vistazine, Rezine)
  • Lasix (furosemide)
  • Levaquin (levofloxacin)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Euthyrox, Unithroid, Levothyrox, Eutroxsig, Levo-T, Oroxine, L Thyroxine Roche, Levotabs, Novothyrox, Tirosint-Sol, Levotec, Evotrox)
  • metformin (Glucophage, Glumetza, Glucophage XR, Fortamet, Riomet)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, RoxyBond, Percolone, Oxecta, Oxydose, Oxyfast, M-Oxy, ETH-Oxydose, Endocodone, Roxicodone Intensol, Dazidox)
  • pantoprazole (Protonix, Protonix IV)
  • pravastatin (Pravachol)
  • prednisone (Deltasone, Rayos, Sterapred, Prednicot, Sterapred DS, Meticorten, Orasone, Liquid Pred, Prednicen-M)
  • Vitamin D3 (cholecalciferol)

Jakafi (ruxolitinib) alcohol/food interactions

There are 2 alcohol/food interactions with Jakafi (ruxolitinib)

Jakafi (ruxolitinib) disease interactions

There are 9 disease interactions with Jakafi (ruxolitinib) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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