Drug Interactions between Prilosec OTC and riluzole
This report displays the potential drug interactions for the following 2 drugs:
- Prilosec OTC (omeprazole)
- riluzole
Interactions between your drugs
omeprazole riluzole
Applies to: Prilosec OTC (omeprazole) and riluzole
Omeprazole may decrease the serum concentration of riluzole. Riluzole is metabolized by the CYP450 1A2 isoenzyme. Omeprazole may induce this particular isoenzyme, possibly increasing the riluzole elimination rate. The clinical significance of this interaction is not known. During coadministration, the patient should be more closely monitored for altered clinical effect.
References (1)
- (2001) "Product Information. Rilutek (riluzole)." Rhone Poulenc Rorer
Drug and food interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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