Drug Interactions between Phenytoin Sodium and piperacillin / tazobactam
This report displays the potential drug interactions for the following 2 drugs:
- Phenytoin Sodium (phenytoin)
- piperacillin/tazobactam
Interactions between your drugs
No interactions were found between Phenytoin Sodium and piperacillin / tazobactam. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Phenytoin Sodium
A total of 843 drugs are known to interact with Phenytoin Sodium.
- Phenytoin sodium is in the following drug classes: group I antiarrhythmics, hydantoin anticonvulsants.
- Phenytoin sodium is used to treat the following conditions:
piperacillin / tazobactam
A total of 55 drugs are known to interact with piperacillin / tazobactam.
- Piperacillin / tazobactam is in the drug class penicillins/beta-lactamase inhibitors.
-
Piperacillin / tazobactam is used to treat the following conditions:
- Appendectomy
- Appendicitis
- Aspiration Pneumonia
- Bacteremia
- Bone infection
- Deep Neck Infection
- Endometritis
- Febrile Neutropenia
- Intraabdominal Infection
- Joint Infection
- Kidney Infections
- Nosocomial Pneumonia
- Pelvic Inflammatory Disease
- Peritonitis
- Pneumonia
- Skin or Soft Tissue Infection
- Urinary Tract Infection
Drug and food interactions
phenytoin food
Applies to: Phenytoin Sodium (phenytoin)
Phenytoin levels may decrease when the suspension is given with enteral feedings. This could lead to a loss of seizure control. You could interrupt the feeding for 2 hours before and after the phenytoin dose. Alternatively, you may give the phenytoin suspension diluted in water and flush the tube with water after administration. These would make it easier for your body to absorb the medication. However, this still may not entirely avoid the interaction and may not always be feasible. You should have your phenytoin levels checked upon starting and stopping of enteral feedings. In addition, using phenytoin together with food may alter the effects of phenytoin. Contact your doctor if you experience worsening of seizure control or symptoms of toxicity, including twitching eye movements, slurred speech, loss of balance, tremor, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Ask your doctor before making any changes to your therapy.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.