Drug Interactions between Phenergan Fortis and Provigil
This report displays the potential drug interactions for the following 2 drugs:
- Phenergan Fortis (promethazine)
- Provigil (modafinil)
Interactions between your drugs
No interactions were found between Phenergan Fortis and Provigil. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Phenergan Fortis
A total of 685 drugs are known to interact with Phenergan Fortis.
- Phenergan fortis is in the following drug classes: antihistamines, phenothiazine antiemetics.
- Phenergan fortis is used to treat the following conditions:
Provigil
A total of 499 drugs are known to interact with Provigil.
- Provigil is in the drug class CNS stimulants.
- Provigil is used to treat the following conditions:
Drug and food interactions
promethazine food
Applies to: Phenergan Fortis (promethazine)
GENERALLY AVOID: Concurrent use of ethanol and phenothiazines may result in additive CNS depression and psychomotor impairment. Also, ethanol may precipitate dystonic reactions in patients who are taking phenothiazines. The two drugs probably act on different sites in the brain, although the exact mechanism of the interaction is not known.
MANAGEMENT: Patients should be advised to avoid alcohol during phenothiazine therapy.
References
- Lutz EG (1976) "Neuroleptic-induced akathisia and dystonia triggered by alcohol." JAMA, 236, p. 2422-3
- Freed E (1981) "Alcohol-triggered-neuroleptic-induced tremor, rigidity and dystonia." Med J Aust, 2, p. 44-5
modafinil food
Applies to: Provigil (modafinil)
Administration with food may delay the absorption of modafinil (the racemate) and armodafinil (the R-enantiomer) without significantly affecting their overall bioavailability. According to the product labeling, modafinil's absorption may be delayed by approximately one hour if taken with food. Similarly, the time to reach peak plasma concentration (Tmax) of armodafinil may be delayed by approximately 2 to 4 hours in the fed state.
References
- (2001) "Product Information. Provigil (modafinil)." Cephalon, Inc
- (2007) "Product Information. Nuvigil (armodafinil)." Cephalon Inc
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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