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Narcan Injection (naloxone) Drug Interactions

A total of 130 drugs are known to interact with Narcan Injection (naloxone).

  • 4 major drug interactions
  • 124 moderate drug interactions
  • 2 minor drug interactions

Show all medications in the database that may interact with Narcan Injection (naloxone).

Check for interactions

Type in a drug name to check for interactions with Narcan Injection (naloxone).

Most frequently checked interactions

View interaction reports for Narcan Injection (naloxone) and the medicines listed below.

  • adenosine (Adenocard, Adenoscan, Adeno-jec, My-O-Den)
  • albuterol (Ventolin HFA, Ventolin, ProAir HFA, Proventil, Proventil HFA, ProAir RespiClick, AccuNeb, Respirol, Volmax, Vospire ER, ProAir Digihaler, Airet)
  • amiodarone (Pacerone, Cordarone, Nexterone, Cordarone IV)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Ascriptin, Bufferin, Fasprin, Arthritis Pain, Easprin, Aspergum, Aspiritab, Halfprin, Empirin, Ascriptin Enteric, Aspirin Lite Coat, Aspi-Cor, Aspirtab, Ecotrin Adult Low Strength, Bayer Children's Aspirin, Buffered Aspirin, Durlaza, Entercote, St. Joseph Aspirin, Acuprin 81, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Migralex, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Bufferin Low Dose, Medi-Seltzer, Sloprin, St. Joseph 81 mg Chewable Aspirin, ZORprin, Low Dose ASA, Bayer Aspirin Extra Strength Plus, Buffex, Ecotrin Maximum Strength, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Ecpirin, Bayer Women's Aspirin With Calcium, Zero-Order Release, YSP Aspirin, Miniprin, Bayer Aspirin Regimen, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Ativan (lorazepam)
  • atropine (AtroPen, Atreza, Sal-Tropine)
  • Benadryl (diphenhydramine)
  • epinephrine (EpiPen, Adrenalin, Primatene Mist, EpiPen 2-Pak, Auvi-Q, EpiPen Auto-Injector, Epi EZ Pen, EpiPen JR 2-Pak, Asthmahaler, Symjepi, EpiPen Jr, Twinject, Adrenaclick, Adrenalin Chloride, Medihaler-Epi, Ana-Guard, Sus-Phrine Injection, EpiPen JR Auto-Injector, Bronitin, Bronchial Mist with Pump, Bronkaid Mist, EPIsnap)
  • fentanyl (Fentanyl Transdermal System, Duragesic, Actiq, Sublimaze, Fentora, Subsys, Abstral, Lazanda, Onsolis, Ionsys)
  • heparin (Heparin Sodium)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Children's Motrin, Proprinal, Motrin IB, Childrens Ibuprofen Berry, Advil Children's, Ibuprofen PMR, Ibu-8, Rufen, IBU-200, Motrin Childrens, Advil Migraine, Caldolor, Ibu-Tab, Menadol, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Pediatric, Genpril, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, Addaprin, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, Motrin Junior Strength, Motrin Infant Drops, NeoProfen, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • Lasix (furosemide)
  • lidocaine (Xylocaine-MPF, Xylocaine Dental Cartridges, Nervocaine, Xylocaine HCl, Lidoject 1, Lidoject 2, Xylocaine Duo-Trach Kit, Xylocaine HCl For Spinal, L-Caine, Dilocaine, Truxacaine, UAD Caine, Anestacaine, DentiPatch)
  • magnesium sulfate (Epsom Salt, Sulfamag)
  • morphine (MS Contin, Morphine Sulfate ER, Morphine Sulfate IR, Roxanol, Kadian, MorphaBond ER, Duramorph, MSIR, Statex, Morphine Sulfate SR, Avinza, Arymo ER, M-Eslon, Astramorph PF, Oramorph SR, Morphine Rapi-Ject, Infumorph, Morphine LP Epidural, RMS, Mitigo, Duramorph PF, OMS, Roxanol 100, Rescudose, MS/S, Roxanol-T, Doloral, Doloral Sirop, Morphitec, M O S)
  • nitroglycerin (Nitrostat, Nitro-Bid, NitroQuick, Nitro-Dur, Tridil, Nitrolingual Pumpspray, Rectiv, Nitro TD Patch-A, Minitran, NitroMist, Nitroglyn E-R, Nitrogard, Nitrostat Tablets, Transderm-Nitro, Nitrol, Nitro-Time, Deponit, Nitrodisc, Nitro-Par, Nitrocot, Nitro-Bid IV, Nitrong, Nitrol Appli-Kit, Nitrek, GoNitro)
  • Phenergan (promethazine)
  • Valium (diazepam)
  • Versed (midazolam)
  • Zofran (ondansetron)

Narcan Injection (naloxone) disease interactions

There are 4 disease interactions with Narcan Injection (naloxone) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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