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Drug Interactions between elacestrant and Sporanox

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

itraconazole elacestrant

Applies to: Sporanox (itraconazole) and elacestrant

Itraconazole may increase the blood levels of elacestrant. This may increase the risk of side effects such as muscle pain, nausea, increased cholesterol, increased liver enzymes, fatigue, decreased hemoglobin, and vomiting. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Major

elacestrant food

Applies to: elacestrant

Elacestrant should be taken with food at approximately the same time each day. Grapefruit, grapefruit juice, and supplements that contain grapefruit, however, may increase the blood levels of elacestrant, which may increase the risk of side effects such as muscle pain, nausea, increased cholesterol, increased liver enzymes, fatigue, decreased hemoglobin, and vomiting. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

itraconazole food

Applies to: Sporanox (itraconazole)

Food increases the absorption of itraconazole capsules but decreases the absorption of itraconazole oral solution. Capsules should be taken immediately after a full meal and the solution be taken on an empty stomach to ensure best results.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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