Can you take Dyclonine / menthol topical with Fesoterodine?
1 drug interaction and 9 additional warnings found for the following 2 drugs:
- dyclonine/menthol topical
- fesoterodine
Drug interactions
Minor drug interactions
Minor:
menthol topical fesoterodine
Applies to: dyclonine / menthol topical and fesoterodine
Information for this minor interaction is available on the professional version.
Food/lifestyle interactions
Moderate food/lifestyle interactions
Moderate:
fesoterodine Food/Lifestyle
Applies to: fesoterodine
Grapefruit juice may increase the levels of fesoterodine in your body. Let your doctor know if you experience excessive drowsiness, dizziness, irregular heartbeat, blurry vision, difficulty urinating, dry mouth, headache, gastrointestinal upset, or constipation while taking fesoterodine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Disease interactions
8 potential interactions Applies to: 8 conditions, including Myasthenia Gravis, Urinary Retention, Liver Disease, Heart Block, and Shock.
Gastrointestinal Obstruction
Major:
fesoterodine
Fesoterodine has a major potential interaction with Gastrointestinal Obstruction.
The use of fesoterodine is contraindicated in patients with gastric retention. Fesoterodine is a competitive muscarinic receptor antagonist and exerts direct antispasmodic effects on smooth muscles. Caution is advised even when using this agent in patients with decreased gastrointestinal motility.
Glaucoma, Narrow Angle
Major:
fesoterodine
Fesoterodine has a major potential interaction with Glaucoma, Narrow Angle.
The use of fesoterodine is contraindicated in patients with uncontrolled narrow-angle glaucoma. Fesoterodine is a competitive muscarinic receptor antagonist. Its use can result in increased intraocular pressure and loss of accommodation. Caution is advised even when using this agent in patients being treated for narrow-angle glaucoma.
Heart Block
Moderate:
dyclonine / menthol topical
The dyclonine topical in dyclonine / menthol topical has a moderate potential interaction with Heart Block.
Dyclonine is absorbed rapidly through intact skin and mucosal membranes following topical administration. Prolonged exposure, large doses, frequent applications and/or use on compromised skin or mucosa can produce systemic toxicity. Cardiovascular adverse effects include depression of myocardium, hypotension, bradycardia, and cardiac arrest. Therapy with dyclonine topical should be administered cautiously in patients with shock, sinus bradyarrhythmia, or severe heart block. The recommended dosage should not be exceeded.
Liver Disease
Moderate:
fesoterodine
Fesoterodine has a moderate potential interaction with Liver Disease.
The use of fesoterodine has not been studied in patients with severe hepatic impairment and therefore is not recommended for use in this patient population. No dose adjustment is recommended in patients with mild or moderate hepatic impairment. Use caution when using this agent in patients with severe hepatic impairment.
Myasthenia Gravis
Moderate:
fesoterodine
Fesoterodine has a moderate potential interaction with Myasthenia Gravis.
Fesoterodine is a competitive muscarinic receptor antagonist. Fesoterodine should be used with caution in patients with myasthenia gravis, a disease characterized by decreased cholinergic activity at the neuromuscular junction.
Renal Dysfunction
Moderate:
fesoterodine
Fesoterodine has a moderate potential interaction with Renal Dysfunction.
Doses of fesoterodine fumarate greater than 4 mg are not recommended in patients with severe renal impairment. No dose adjustment is recommended in patients with mild or moderate renal impairment.
Shock
Moderate:
dyclonine / menthol topical
The dyclonine topical in dyclonine / menthol topical has a moderate potential interaction with Shock.
Dyclonine is absorbed rapidly through intact skin and mucosal membranes following topical administration. Prolonged exposure, large doses, frequent applications and/or use on compromised skin or mucosa can produce systemic toxicity. Cardiovascular adverse effects include depression of myocardium, hypotension, bradycardia, and cardiac arrest. Therapy with dyclonine topical should be administered cautiously in patients with shock, sinus bradyarrhythmia, or severe heart block. The recommended dosage should not be exceeded.
Urinary Retention
Major:
fesoterodine
Fesoterodine has a major potential interaction with Urinary Retention.
The use of fesoterodine is contraindicated in patients with urinary retention. Fesoterodine is a competitive muscarinic receptor antagonist and exerts direct antispasmodic effects on smooth muscles. Caution is advised even when using this agent in patients with clinically significant bladder outlet obstruction because of the risk of urinary retention.
Report options
More resources
dyclonine / menthol topical
A total of 364 drugs are known to interact with dyclonine / menthol topical.
- Dyclonine / menthol topical is in the drug class mouth and throat products.
- Dyclonine / menthol topical is used to treat the following conditions:
fesoterodine
A total of 355 drugs are known to interact with fesoterodine.
- Fesoterodine is in the drug class urinary antispasmodics.
- Fesoterodine is used to treat the following conditions:
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.