Benadryl Drug Interactions
Currently displaying 14 drugs known to have a major interaction with Benadryl (diphenhydramine).
- 14 major drug interactions
- 432 moderate drug interactions
- 2 minor drug interactions
Major interactions with Benadryl (diphenhydramine)
Note: Showing generic names only.
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Benadryl alcohol/food interactions
There is 1 alcohol/food interaction with Benadryl (diphenhydramine).
Benadryl disease interactions
There are 8 disease interactions with Benadryl (diphenhydramine) which include:
- depression
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
More about Benadryl (diphenhydramine)
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- Drug class: anticholinergic antiemetics
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.