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Defibrotide Drug Interactions

A total of 199 drugs are known to interact with defibrotide.

  • 96 major drug interactions
  • 97 moderate drug interactions
  • 6 minor drug interactions

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Medications known to interact with defibrotide

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    • ibritumomab (In-111 Zevalin, Y-90 Zevalin, Zevalin)
    • ibrutinib (Imbruvica)
    • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Children's Motrin, Proprinal, Motrin IB, Childrens Ibuprofen Berry, Advil Children's, Ibuprofen PMR, Ibu-8, Rufen, IBU-200, Motrin Childrens, Advil Migraine, Caldolor, Ibu-Tab, Menadol, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Pediatric, Genpril, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, Addaprin, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, Motrin Junior Strength, Motrin Infant Drops, NeoProfen, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
    • ibuprofen / oxycodone (Combunox)
    • ibuprofen / phenylephrine (Advil Congestion Relief, Advil Sinus Congestion & Pain)
    • ibuprofen / pseudoephedrine (Advil Cold and Sinus, Advil Cold and Sinus Liqui-Gels, Dristan Sinus, Motrin IB Sinus, Sine-Aid IB, Motrin Cold and Flu, Motrin Childrens Cold, Motrin Sinus Headache, Advil Children's Cold)
    • icosapent (Vascepa)
    • iloprost (Ventavis)
    • indomethacin (Indocin, Indocin SR, Tivorbex, Indocin IV)
    • inotersen (Tegsedi)
    • iodine i 131 tositumomab (Bexxar)
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    • nabumetone (Relafen)
    • naproxen (Aleve, Naprosyn, Naproxen Sodium DS, Anaprox, Naprelan, Anaprox-DS, EC-Naprosyn, Midol Extended Relief, Flanax Pain Reliever, Comfort Pac with Naproxen, Leader Naproxen Sodium, Aflaxen, Pamprin All Day Relief, All Day Pain Relief, All Day Relief)
    • naproxen / pseudoephedrine (Aleve-D Sinus & Cold, Sinus & Cold D, Sudafed 12 Hour Pressure+Pain, Aleve-D Sinus & Headache)
    • naproxen / sumatriptan (Treximet)
    • nepafenac ophthalmic (Ilevro, Nevanac)
    • nintedanib (Ofev)
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    • omacetaxine (Synribo)
    • omega-3 polyunsaturated fatty acids (Lovaza, Fish Oil, Omega-3, Omega 3-6-9 Complex, Nature's Bounty Red Krill Oil, Omega-500, Vayarin, Prenatal DHA, MegaKrill, Omacor, Fish Oil Ultra, Epanova, Marine Lipid Concentrate, MaxEPA, Omega Essentials, Vascazen, TheraTears Nutrition, Animi-3 with Vitamin D, Dry Eye Omega Benefits, Systane Vitamin Omega-3 Healthy Tears, MaxiTears Dry Eye Formula, Sea-Omega, Super-EPA, Proepa, EPA Fish Oil, Icar Prenatal Essential Omega-3, Sea-Omega 30, Sea-Omega 70, Animi-3, Mi-Omega NF, Omega Essentials Basic, Mi-Omega, Wellbaby DHA, Divista, Ovega-3 Vegetarian, MaxiVision Omega-3 Formula, TherOmega, Omtryg, Cardio Omega Benefits, Flex Omega Benefits, Sundown Naturals Triple Strength Red Krill Oil, Triklo, Mom's Omega Advantage, TherOmega Sport, Dialyvite Omega-3 Concentrate, Maximum Red Krill)
    • oxaprozin (Daypro, Daypro Alta)
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    Defibrotide disease interactions

    There is 1 disease interaction with defibrotide:

    Drug Interaction Classification

    These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
    Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
    Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
    Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
    Unknown No interaction information available.

    Further information

    Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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