Cotellic Drug Interactions
Currently displaying 251 drugs known to have a moderate interaction with Cotellic (cobimetinib).
- 117 major drug interactions
- 251 moderate drug interactions
Moderate interactions with Cotellic (cobimetinib)
Note: Showing generic names only.
A
- abametapir topical
- abiraterone
- abrocitinib
- adenovirus vaccine
- alefacept
- alemtuzumab
- alpelisib
- aminoglutethimide
- aminolevulinic acid topical
- amiodarone
- amlodipine
- amobarbital
- anakinra
- anthrax vaccine adsorbed
- armodafinil
- asciminib
- avacopan
- azathioprine
B
- bedaquiline
- bepridil
- bexarotene
- bicalutamide
- bifidobacterium infantis
- black cohosh
- brentuximab
- brewer's yeast
- brigatinib
- butabarbital
- butalbital
C
- cabozantinib
- canakinumab
- candida albicans extract
- cannabidiol
- capivasertib
- capmatinib
- chloramphenicol
- cholera vaccine
- cholera vaccine, live
- cimetidine
- clofarabine
- clotrimazole
- coccidioidin skin test
- cyclosporine
D
- daclatasvir
- daclizumab
- danazol
- danicopan
- dasatinib
- deferasirox
- denosumab
- dimethyl fumarate
- diroximel fumarate
E
- echinacea
- efalizumab
- elacestrant
- elagolix
- eliglustat
- encorafenib
- entrectinib
- epirubicin
- erdafitinib
- ezogabine
F
G
H
- haemophilus b conjugate (hboc) vaccine
- haemophilus b conjugate (prp-omp) vaccine
- haemophilus b conjugate (prp-t) vaccine
- hepatitis a adult vaccine
- hepatitis a pediatric vaccine
- hepatitis b adult vaccine
- hepatitis b pediatric vaccine
- histoplasmin
- human papillomavirus vaccine
I
- influenza virus vaccine, h1n1, inactivated
- influenza virus vaccine, h5n1
- influenza virus vaccine, inactivated
- interferon beta-1a
- interferon beta-1b
- isoniazid
- istradefylline
- ivacaftor
- ivosidenib
J
L
- lactobacillus acidophilus
- lactobacillus reuteri
- lactobacillus rhamnosus
- lactobacillus rhamnosus gg
- lapatinib
- larotrectinib
- lasmiditan
- lefamulin
- lenacapavir
- levamlodipine
- lonapegsomatropin
- lyme disease vaccine
M
- mavacamten
- meningococcal conjugate vaccine
- meningococcal group acwy conjugate-group b vaccine (cvx 316)
- meningococcal group B vaccine
- meningococcal polysaccharide vaccine
- mephobarbital
- methotrexate
- methoxsalen
- methyl aminolevulinate topical
- metreleptin
- miconazole
- midostaurin
- mitapivat
- mixed respiratory vaccine
- mobocertinib
- monomethyl fumarate
- mumps skin test antigen
N
O
P
- pacritinib
- palbociclib
- palifermin
- pazopanib
- peginterferon beta-1a
- pemigatinib
- pentobarbital
- pertussis, acellular
- phenylbutazone
- pirtobrutinib
- plague vaccine
- pneumococcal 13-valent vaccine
- pneumococcal 15-valent conjugate vaccine
- pneumococcal 20-valent conjugate vaccine
- pneumococcal 23-polyvalent vaccine
- pneumococcal 7-valent vaccine
- poliovirus vaccine, inactivated
- ponatinib
- porfimer
- pralsetinib
Q
R
- rabies vaccine, human diploid cell
- rabies vaccine, purified chick embryo cell
- ranolazine
- remdesivir
- rilonacept
- ripretinib
- risdiplam
- roflumilast
- rolapitant
- ropeginterferon alfa-2b
- rsv vaccine pref3, recombinant
- rsv vaccine, pref a-pref b, recombinant
- rucaparib
- rufinamide
S
- saccharomyces boulardii lyo
- sarecycline
- sars-cov-2 (covid-19) ad26 vaccine, recombinant
- sars-cov-2 (covid-19) chadox1 vaccine, recombinant
- sars-cov-2 (covid-19) mrna (tozinameran 12y+) bivalent booster vaccine
- sars-cov-2 (covid-19) mrna (tozinameran 5y-11y) bivalent booster vaccine
- sars-cov-2 (covid-19) mrna (tozinameran 6m-4y) bivalent booster vaccine
- sars-cov-2 (covid-19) mrna (tozinameran 6m-4y) bivalent vaccine
- sars-cov-2 (covid-19) mrna-1273 (6m-5y bivalent booster) vaccine
- sars-cov-2 (covid-19) mrna-1273 (bivalent booster) vaccine
- sars-cov-2 (covid-19) mrna-1273 bivalent vaccine
- sars-cov-2 (covid-19) mrna-1273 vaccine
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 311)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 312)
- sars-cov-2 (covid-19) mrna(tozinameran12y+) bivalent vaccine
- sars-cov-2 (covid-19) nvx-cov2373 vaccine, recombinant
- sars-cov-2 (covid-19) rs-nanoparticle vaccine, recombinant
- sars-cov-2 (covid-19)mrna-1273(6y+ bivalent booster) vaccine
- sars-cov-2 mrna (tozinameran 5y-11y) vaccine
- sars-cov-2 mrna (tozinameran 6m-4y) vaccine
- sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine
- sars-cov-2 mrna (tozinameran) vaccine
- sars-cov-2 mrna-1273 (6m-5y) vaccine
- sars-cov-2 mrna-1273 (6y-11y) vaccine
- sars-cov-2 mrna-1273 (booster only) vaccine
- sars-cov-2 nvx-cov2373 vaccine, recomb (cvx 313)
- sars-cov-2 pres dtm (booster only) vaccine, recombinant
- sars-cov-2(covid-19)mrna(tozinameran 5y-11y)bivalent vaccine
- secobarbital
- selpercatinib
- simeprevir
- sipuleucel-T
- skin test antigens, multiple
- smallpox and monkeypox vaccine
- sodium phosphate p32
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotorasib
- sparsentan
- spironolactone
- staphage lysate (spl)
- sulfinpyrazone
- suvorexant
T
- tacrolimus
- tamoxifen
- tazemetostat
- tecovirimat
- tepotinib
- tetanus toxoid
- thioguanine
- ticagrelor
- tick-borne encephalitis (inactivated) pediatric vaccine
- tick-borne encephalitis (inactivated) vaccine
- tolvaptan
- topotecan
- trabectedin
- trichophyton skin test
- trofinetide
- troglitazone
- tuberculin purified protein derivative
- typhoid vaccine, inactivated
U
V
Z
Cotellic alcohol/food interactions
There is 1 alcohol/food interaction with Cotellic (cobimetinib).
Cotellic disease interactions
There are 7 disease interactions with Cotellic (cobimetinib) which include:
- cardiomyopathy
- hepatotoxicity
- ocular toxicities
- rhabdomyolysis
- lung toxicity
- liver dysfunction
- renal impairment
More about Cotellic (cobimetinib)
- Cotellic consumer information
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- FDA approval history
- Drug class: multikinase inhibitors
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Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.