RCK Interactions
There are 880 drugs known to interact with RCK (clonidine / ketorolac / ropivacaine), along with 16 disease interactions, and 4 alcohol/food interactions. Of the total drug interactions, 169 are major, 633 are moderate, and 78 are minor.
- View RCK alcohol/food interactions (4)
- View RCK disease interactions (16)
Medications known to interact with RCK
Note: Showing generic names only.
A
- abametapir topical
- abciximab
- abrocitinib
- acalabrutinib
- acebutolol
- acetaminophen
- acetohexamide
- acetylcarbromal
- acrivastine
- adagrasib
- adefovir
- ado-trastuzumab emtansine
- aldesleukin
- alemtuzumab
- alendronate
- alfentanil
- aliskiren
- allopurinol
- alprazolam
- alteplase
- ambenonium
- amifostine
- amikacin
- amikacin liposome
- amiloride
- aminosalicylic acid
- amiodarone
- amisulpride
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amprenavir
- amyl nitrite
- anagrelide
- anisindione
- anistreplase
- antithrombin (recombinant)
- antithrombin iii
- apixaban
- apomorphine
- apraclonidine ophthalmic
- aprepitant
- ardeparin
- argatroban
- aripiprazole
- asciminib
- asenapine
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- aspirin
- atazanavir
- atenolol
- atovaquone
- atracurium
- avacopan
- avanafil
- avapritinib
- azatadine
- azelastine nasal
- azilsartan medoxomil
B
- baclofen
- balsalazide
- baricitinib
- bedaquiline
- belzutifan
- benazepril
- bendroflumethiazide
- benoxinate ophthalmic
- benzgalantamine
- benzocaine topical
- benzthiazide
- benztropine
- bepridil
- berotralstat
- betamethasone
- betaxolol
- betaxolol ophthalmic
- betiatide
- betrixaban
- bexagliflozin
- bicalutamide
- biperiden
- bisoprolol
- bivalirudin
- black cohosh
- boceprevir
- botulism immune globulin
- brentuximab
- bretylium
- brexanolone
- brexpiprazole
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromfenac
- bromocriptine
- brompheniramine
- budesonide
- bumetanide
- bupivacaine
- bupivacaine liposome
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cabergoline
- cabozantinib
- caffeine
- calaspargase pegol
- canagliflozin
- candesartan
- cangrelor
- cannabidiol
- cannabis
- capivasertib
- caplacizumab
- capmatinib
- captopril
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- carteolol
- carteolol ophthalmic
- carvedilol
- celecoxib
- cenobamate
- ceritinib
- cetirizine
- chlophedianol
- chloral hydrate
- chloramphenicol
- chlorcyclizine
- chlordiazepoxide
- chlormezanone
- chloroprocaine
- chloroprocaine ophthalmic
- chloroquine
- chlorothiazide
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorpropamide
- chlorthalidone
- chlorzoxazone
- choline salicylate
- cidofovir
- cilostazol
- cimetidine
- cinoxacin
- ciprofloxacin
- cisatracurium
- citalopram
- clarithromycin
- clemastine
- clobazam
- clofarabine
- clomipramine
- clonazepam
- clopidogrel
- clorazepate
- clotrimazole
- clove
- clozapine
- cobicistat
- cocaine nasal
- cocaine topical
- codeine
- conivaptan
- corticorelin
- corticotropin
- cortisone
- cosyntropin
- crizotinib
- cyclizine
- cyclobenzaprine
- cyclophosphamide
- cyclosporine
- cyproheptadine
- cytomegalovirus immune globulin
D
- dabigatran
- daclizumab
- dalteparin
- danaparoid
- danazol
- dantrolene
- dapagliflozin
- daprodustat
- dapsone
- dapsone topical
- daptomycin
- daridorexant
- darunavir
- dasatinib
- deferasirox
- defibrotide
- deflazacort
- delafloxacin
- delavirdine
- deserpidine
- desipramine
- desirudin
- desmopressin
- desvenlafaxine
- deutetrabenazine
- dexamethasone
- dexbrompheniramine
- dexfenfluramine
- dexmedetomidine
- dexmethylphenidate
- dextromethorphan
- dezocine
- diatrizoate
- diazepam
- dibucaine topical
- diclofenac
- diclofenac topical
- dicumarol
- difelikefalin
- diflunisal
- digitoxin
- digoxin
- diltiazem
- dimenhydrinate
- dimethyl fumarate
- diphenhydramine
- dipyridamole
- diroximel fumarate
- disopyramide
- divalproex sodium
- dofetilide
- donepezil
- doxacurium
- doxazosin
- doxepin
- doxepin topical
- doxylamine
- dronabinol
- dronedarone
- droperidol
- drospirenone
- drotrecogin alfa
- duloxetine
- duvelisib
E
- echinacea
- edoxaban
- edrophonium
- efavirenz
- empagliflozin
- enalapril
- enalaprilat
- enoxacin
- enoxaparin
- entacapone
- entecavir
- entrectinib
- epirubicin
- eplerenone
- epoprostenol
- eprosartan
- eptifibatide
- erlotinib
- ertugliflozin
- erythromycin
- escitalopram
- esketamine
- eslicarbazepine
- esmolol
- estazolam
- eszopiclone
- ethacrynic acid
- ethanol
- ethchlorvynol
- ethinyl estradiol
- ethosuximide
- ethotoin
- etidocaine
- etidronate
- etodolac
- etranacogene dezaparvovec
- etrasimod
- everolimus
- exenatide
- ezogabine
F
- famotidine
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fenoldopam
- fenoprofen
- fentanyl
- fexinidazole
- fidanacogene elaparvovec
- finerenone
- flavoxate
- flecainide
- flibanserin
- fluconazole
- flucytosine
- fludrocortisone
- fluoxetine
- fluphenazine
- flurazepam
- flurbiprofen
- flutamide
- fluvoxamine
- fondaparinux
- fosamprenavir
- fosaprepitant
- fosinopril
- fosphenytoin
- fospropofol
- fostamatinib
- furazolidone
- furosemide
G
- gabapentin
- gabapentin enacarbil
- galantamine
- ganaxolone
- ganciclovir
- garlic
- gatifloxacin
- gemifloxacin
- gentamicin
- ginkgo
- givosiran
- glimepiride
- glipizide
- glyburide
- grepafloxacin
- guanabenz
- guanadrel
- guanethidine
- guanfacine
- guanidine
H
- halazepam
- haloperidol
- heparin
- heparin flush
- heroin
- horse chestnut
- house dust mite allergen extract
- hyaluronidase
- hydralazine
- hydrochlorothiazide
- hydrocodone
- hydrocortisone
- hydroflumethiazide
- hydromorphone
- hydroxychloroquine
- hydroxyprogesterone
- hydroxyurea
- hydroxyzine
I
- ibandronate
- ibritumomab
- ibrutinib
- ibuprofen
- ibutilide
- icosapent
- idelalisib
- ifosfamide
- iloperidone
- iloprost
- imatinib
- imipramine
- immune globulin intravenous
- immune globulin intravenous and subcutaneous
- indapamide
- indinavir
- indomethacin
- inotersen
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- interferon beta-1a
- interferon beta-1b
- iodamide
- iodine i 131 tositumomab
- iodipamide
- iodixanol
- iohexol
- iomeprol
- iopamidol
- iopromide
- iothalamate
- ioversol
- ioxaglate
- ioxilan
- irbesartan
- isavuconazonium
- isocarboxazid
- isoniazid
- isosorbide
- isosorbide dinitrate
- isosorbide mononitrate
- isradipine
- itraconazole
K
L
- labetalol
- lamotrigine
- landiolol
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lefamulin
- leflunomide
- lemborexant
- lenacapavir
- leniolisib
- lepirudin
- letermovir
- levamlodipine
- levetiracetam
- levobetaxolol ophthalmic
- levobunolol ophthalmic
- levobupivacaine
- levocetirizine
- levodopa
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- levorphanol
- licorice
- lidocaine
- lidocaine ophthalmic
- lidocaine otic
- lidocaine topical
- linaclotide
- linezolid
- lisinopril
- lithium
- lofexidine
- lomefloxacin
- lomitapide
- lonafarnib
- lonapegsomatropin
- lorazepam
- lorlatinib
- losartan
- loxapine
- lumateperone
- lurasidone
- lvp solution with potassium
M
- macimorelin
- mafenide topical
- magnesium salicylate
- maprotiline
- maraviroc
- mavorixafor
- mecamylamine
- meclizine
- meclofenamate
- mefenamic acid
- melatonin
- meloxicam
- meperidine
- mephenytoin
- mephobarbital
- mepivacaine
- meprobamate
- mesalamine
- mesoridazine
- metaxalone
- metformin
- methadone
- methdilazine
- methocarbamol
- methohexital
- methotrexate
- methotrimeprazine
- methoxyflurane
- methsuximide
- methyclothiazide
- methyldopa
- methylphenidate
- methylprednisolone
- metipranolol ophthalmic
- metoclopramide
- metocurine
- metolazone
- metoprolol
- metrizamide
- metyrosine
- mexiletine
- mibefradil
- miconazole
- midazolam
- mifepristone
- milnacipran
- mipomersen
- mirtazapine
- mitotane
- mivacurium
- mixed grass pollens allergen extract
- moexipril
- molindone
- monomethyl fumarate
- moricizine
- morphine
- morphine liposomal
- moxifloxacin
N
- nabilone
- nabumetone
- nadolol
- nalbuphine
- nalidixic acid
- naltrexone
- naproxen
- nateglinide
- nebivolol
- nefazodone
- nelfinavir
- neostigmine
- netilmicin
- nevirapine
- nicardipine
- nicotine
- nifedipine
- nilotinib
- nimodipine
- nintedanib
- niraparib
- nirogacestat
- nisoldipine
- nitric oxide
- nitrofurantoin
- nitroglycerin
- nitroprusside
- nitrous oxide
- nizatidine
- norfloxacin
- nortriptyline
O
- obeticholic acid
- ofloxacin
- olanzapine
- olaparib
- oliceridine
- olmesartan
- olopatadine nasal
- olsalazine
- olutasidenib
- omacetaxine
- omaveloxolone
- omega-3 polyunsaturated fatty acids
- opicapone
- opium
- orphenadrine
- osilodrostat
- oxaliplatin
- oxaprozin
- oxazepam
- oxcarbazepine
- oxycodone
- oxymorphone
- ozanimod
P
- pacritinib
- palbociclib
- paliperidone
- pamidronate
- pancuronium
- panobinostat
- paraldehyde
- paramethadione
- paroxetine
- pazopanib
- peanut allergen powder
- pegaspargase
- peginterferon beta-1a
- pemetrexed
- penbutolol
- pentazocine
- pentobarbital
- pentoxifylline
- perampanel
- pergolide
- perindopril
- perphenazine
- pexidartinib
- phenacemide
- phenazopyridine
- phenelzine
- phenindamine
- phenobarbital
- phenoxybenzamine
- phensuximide
- phentolamine
- phenylbutazone
- phenytoin
- physostigmine
- pimozide
- pindolol
- pipecuronium
- piroxicam
- pirtobrutinib
- pitolisant
- plasminogen, human
- plazomicin
- polyethylene glycol 3350 with electrolytes
- polythiazide
- ponatinib
- ponesimod
- posaconazole
- potassium acid phosphate
- potassium aminobenzoate
- potassium bicarbonate
- potassium chloride
- potassium citrate
- potassium gluconate
- potassium iodide
- potassium perchlorate
- potassium phosphate
- pralatrexate
- pralsetinib
- pramipexole
- pramoxine topical
- prasugrel
- prazosin
- prednisolone
- prednisone
- pregabalin
- prilocaine
- primaquine
- primidone
- probenecid
- procainamide
- procaine
- procaine penicillin
- procarbazine
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propafenone
- proparacaine ophthalmic
- propiomazine
- propofol
- propoxyphene
- propranolol
- protriptyline
- pyridostigmine
- pyrilamine
Q
R
- ragweed pollen allergen extract
- ramelteon
- ramipril
- ramucirumab
- ranitidine
- ranitidine bismuth citrate
- ranolazine
- rapacuronium
- rasagiline
- rasburicase
- rauwolfia serpentina
- regorafenib
- remdesivir
- remifentanil
- remimazolam
- repaglinide
- repotrectinib
- reserpine
- respiratory syncytial virus immune globulin
- reteplase
- revakinagene taroretcel
- rho (d) immune globulin
- ribociclib
- rifabutin
- rifampin
- rifapentine
- riluzole
- riociguat
- risedronate
- risperidone
- ritlecitinib
- ritonavir
- rivaroxaban
- rivastigmine
- rocuronium
- rofecoxib
- ropinirole
- rotigotine
- rucaparib
- rufinamide
- ruxolitinib
S
- safinamide
- salsalate
- saquinavir
- scopolamine
- secobarbital
- selegiline
- selexipag
- selpercatinib
- sertraline
- sibutramine
- sildenafil
- silver nitrate topical
- silver sulfadiazine topical
- sirolimus
- sodium nitrite
- sodium oxybate
- sodium salicylate
- sodium thiosalicylate
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotagliflozin
- sotalol
- sparfloxacin
- sparsentan
- spironolactone
- st. john's wort
- stiripentol
- streptokinase
- streptomycin
- succinylcholine
- sufentanil
- sulfadiazine
- sulfamethizole
- sulfamethoxazole
- sulfasalazine
- sulfinpyrazone
- sulfisoxazole
- sulindac
- suvorexant
T
- tacrine
- tacrolimus
- tadalafil
- tafasitamab
- tafenoquine
- tapentadol
- tasimelteon
- taurine
- tazemetostat
- telaprevir
- telbivudine
- telithromycin
- telmisartan
- temazepam
- temsirolimus
- tenecteplase
- tenofovir alafenamide
- tenofovir disoproxil
- terazosin
- terbinafine
- teriflunomide
- tetrabenazine
- tetracaine
- tetracaine ophthalmic
- tetracaine topical
- thalidomide
- theophylline
- thiethylperazine
- thioguanine
- thiopental
- thioridazine
- thiothixene
- tiagabine
- ticagrelor
- ticlopidine
- tilmanocept
- tiludronate
- timolol
- timolol ophthalmic
- timothy grass pollen allergen extract
- tinzaparin
- tirofiban
- tizanidine
- tobramycin
- tocainide
- tofacitinib
- tolazamide
- tolazoline
- tolbutamide
- tolcapone
- tolmetin
- topiramate
- torsemide
- tositumomab
- tovorafenib
- trabectedin
- tramadol
- trandolapril
- tranylcypromine
- trazodone
- treosulfan
- treprostinil
- triamcinolone
- triamcinolone ophthalmic
- triamterene
- triazolam
- trichlormethiazide
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethaphan camsylate
- trimethobenzamide
- trimethoprim
- trimipramine
- tripelennamine
- triprolidine
- trofinetide
- troleandomycin
- trospium
- trovafloxacin
- tubocurarine
- tucatinib
- turmeric
U
V
- vadadustat
- valacyclovir
- valbenazine
- valdecoxib
- valerian
- valganciclovir
- valoctocogene roxaparvovec
- valproic acid
- valsartan
- vamorolone
- vancomycin
- vardenafil
- varenicline
- vasopressin
- vecuronium
- vemurafenib
- venlafaxine
- verapamil
- vericiguat
- verteporfin
- vigabatrin
- vilazodone
- viloxazine
- voclosporin
- vonoprazan
- vorapaxar
- vorasidenib
- voriconazole
- vortioxetine
- vosoritide
- voxelotor
W
Z
- zafirlukast
- zaleplon
- zanubrutinib
- ziconotide
- zidovudine
- ziprasidone
- zoledronic acid
- zolpidem
- zonisamide
- zuranolone
RCK alcohol/food interactions
There are 4 alcohol/food interactions with RCK (clonidine / ketorolac / ropivacaine).
RCK disease interactions
There are 16 disease interactions with RCK (clonidine / ketorolac / ropivacaine) which include:
- GI toxicity
- platelet aggregation inhibition
- renal dysfunction
- asthma
- fluid retention
- GI toxicity
- rash
- thrombosis
- bradyarrhythmia
- depression
- hypotension
- renal dysfunction
- sedatives/alcohol
- anemia
- hepatotoxicity
- hyperkalemia
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.