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Drug Interactions between chlorpromazine and Thorazine

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

No interactions were found between chlorpromazine and Thorazine. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

chlorpromazine

A total of 718 drugs are known to interact with chlorpromazine.

Thorazine

A total of 718 drugs are known to interact with Thorazine.

Drug and food interactions

Moderate

chlorproMAZINE food

Applies to: chlorpromazine and Thorazine (chlorpromazine)

GENERALLY AVOID: Concurrent use of ethanol and phenothiazines may result in additive CNS depression and psychomotor impairment. Also, ethanol may precipitate dystonic reactions in patients who are taking phenothiazines. The two drugs probably act on different sites in the brain, although the exact mechanism of the interaction is not known.

MANAGEMENT: Patients should be advised to avoid alcohol during phenothiazine therapy.

References

  1. Lutz EG "Neuroleptic-induced akathisia and dystonia triggered by alcohol." JAMA 236 (1976): 2422-3
  2. Freed E "Alcohol-triggered-neuroleptic-induced tremor, rigidity and dystonia." Med J Aust 2 (1981): 44-5

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Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Antidopaminergic-like antiemetics

Therapeutic duplication

The recommended maximum number of medicines in the 'antidopaminergic-like antiemetics' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'antidopaminergic-like antiemetics' category:

  • chlorpromazine
  • Thorazine (chlorpromazine)

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.

Duplication

Antiemetics

Therapeutic duplication

The recommended maximum number of medicines in the 'antiemetics' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'antiemetics' category:

  • chlorpromazine
  • Thorazine (chlorpromazine)

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.

Duplication

Antipsychotics

Therapeutic duplication

The recommended maximum number of medicines in the 'antipsychotics' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'antipsychotics' category:

  • chlorpromazine
  • Thorazine (chlorpromazine)

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.

Duplication

Antivertigo agents

Therapeutic duplication

The recommended maximum number of medicines in the 'antivertigo agents' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'antivertigo agents' category:

  • chlorpromazine
  • Thorazine (chlorpromazine)

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer