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Can you take Cervarix with Delgocitinib topical?

1 drug interaction and 6 additional warnings found for the following 2 drugs:

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Drug interactions

Moderate drug interactions

Moderate:

human papillomavirus vaccine delgocitinib topical

Applies to: Cervarix (human papillomavirus vaccine) and delgocitinib topical

If you are currently being treated or have recently been treated with delgocitinib topical, you should let your doctor know before receiving human papillomavirus vaccine. Depending on the dose and length of time you have been on delgocitinib topical, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of delgocitinib topical therapy. If you have recently been vaccinated with human papillomavirus vaccine, your doctor may choose to postpone treatment with delgocitinib topical for a couple of weeks or more. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food/lifestyle interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease interactions

6 potential interactions Applies to: 6 conditions, including Hypotension, Fever, Syncope, Infection, and Dehydration.

Dehydration

Moderate:

Cervarix

The human papillomavirus vaccine in Cervarix has a moderate potential interaction with Dehydration.

The administration of human papillomavirus vaccine has been associated with syncope, sometimes resulting in falling with injury. The syncope sometimes is associated with tonic-clonic movements and other seizure-like activity. Caution is recommended when administering the vaccine to individuals susceptible to syncope. Observation for 15 minutes is recommended after its administration.

Fever

Major:

Cervarix

The human papillomavirus vaccine in Cervarix has a major potential interaction with Fever.

Ideally, vaccination should occur when an individual is healthy, thus minimizing the risk of an adverse host reaction and/or vaccine failure. However, a current or recent infection does not necessarily preclude the use of vaccines, depending on the severity of the patient's symptoms and their etiology. Superficial infections and minor acute illnesses such as a mild upper respiratory infection with or without low-grade fever do not contraindicate immunization, particularly if prompt administration of a vaccine is deemed necessary or beneficial. In fact, when vaccines are administered during the course of a minor illness, the risk of adverse events is not increased, and serum antibody response is not often diminished. On the other hand, if fever or symptoms suggest a moderate or severe illness, it is usually appropriate to withhold vaccination until the patient has recovered. In addition to the potential risks already mentioned, evolving signs and symptoms of the illness can sometimes confound the diagnosis of a vaccine reaction if it develops. In the presence of any infection, the decision to administer or withhold/defer immunization should take into consideration the benefits versus the risks to an individual patient.

Hypotension

Moderate:

Cervarix

The human papillomavirus vaccine in Cervarix has a moderate potential interaction with Hypotension.

The administration of human papillomavirus vaccine has been associated with syncope, sometimes resulting in falling with injury. The syncope sometimes is associated with tonic-clonic movements and other seizure-like activity. Caution is recommended when administering the vaccine to individuals susceptible to syncope. Observation for 15 minutes is recommended after its administration.

Immunodeficiency

Moderate:

Cervarix

The human papillomavirus vaccine in Cervarix has a moderate potential interaction with Immunodeficiency.

The expected serum antibody responses may not be obtained when vaccines and/or toxoids are administered to patients with primary or acquired immunodeficiency, including those with severe combined immunodeficiency, hypogammaglobulinemia or agammaglobulinemia, HIV infection, altered immune states (due to diseases such as leukemia, lymphoma, or generalized malignancy), or immunosuppression due to drug or other treatments (e.g., corticosteroids, alkylating agents, antimetabolites, or radiation).

Infection

Major:

Cervarix

The human papillomavirus vaccine in Cervarix has a major potential interaction with Infection.

Ideally, vaccination should occur when an individual is healthy, thus minimizing the risk of an adverse host reaction and/or vaccine failure. However, a current or recent infection does not necessarily preclude the use of vaccines, depending on the severity of the patient's symptoms and their etiology. Superficial infections and minor acute illnesses such as a mild upper respiratory infection with or without low-grade fever do not contraindicate immunization, particularly if prompt administration of a vaccine is deemed necessary or beneficial. In fact, when vaccines are administered during the course of a minor illness, the risk of adverse events is not increased, and serum antibody response is not often diminished. On the other hand, if fever or symptoms suggest a moderate or severe illness, it is usually appropriate to withhold vaccination until the patient has recovered. In addition to the potential risks already mentioned, evolving signs and symptoms of the illness can sometimes confound the diagnosis of a vaccine reaction if it develops. In the presence of any infection, the decision to administer or withhold/defer immunization should take into consideration the benefits versus the risks to an individual patient.

Syncope

Moderate:

Cervarix

The human papillomavirus vaccine in Cervarix has a moderate potential interaction with Syncope.

The administration of human papillomavirus vaccine has been associated with syncope, sometimes resulting in falling with injury. The syncope sometimes is associated with tonic-clonic movements and other seizure-like activity. Caution is recommended when administering the vaccine to individuals susceptible to syncope. Observation for 15 minutes is recommended after its administration.

More resources

Cervarix

A total of 340 drugs are known to interact with Cervarix.

delgocitinib topical

A total of 334 drugs are known to interact with delgocitinib topical.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.