Marcaine HCl Interactions
There are 139 drugs known to interact with Marcaine HCl (bupivacaine), along with 3 disease interactions. Of the total drug interactions, 23 are major, 111 are moderate, and 5 are minor.
- View all 139 medications that may interact with Marcaine HCl
- View Marcaine HCl disease interactions (3)
Most frequently checked interactions
View interaction reports for Marcaine HCl (bupivacaine) and the medicines listed below.
- acetaminophen / oxycodone
- Adderall (amphetamine / dextroamphetamine)
- Aimovig (erenumab)
- albuterol
- Ambien (zolpidem)
- amoxicillin
- amoxicillin / clavulanate
- baclofen
- Benadryl (diphenhydramine)
- cyclobenzaprine
- diazepam
- doxycycline
- EpiPen (epinephrine)
- famotidine
- ibuprofen
- lidocaine
- Lyrica (pregabalin)
- meloxicam
- montelukast
- naproxen
- omeprazole
- ondansetron
- oxycodone
- Percocet 5 / 325 (acetaminophen / oxycodone)
- prednisone
- tramadol
- Tylenol Extra Strength (acetaminophen)
- Vitamin D3 (cholecalciferol)
- Zofran (ondansetron)
- Zyrtec (cetirizine)
Marcaine HCl disease interactions
There are 3 disease interactions with Marcaine HCl (bupivacaine) which include:
Report options
More about Marcaine HCl (bupivacaine)
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- Latest FDA alerts (6)
- Side effects
- Dosage information
- During pregnancy
- Drug class: local injectable anesthetics
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.