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Drug Interactions between aspirin / omeprazole and Plavix

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

omeprazole clopidogrel

Applies to: aspirin / omeprazole and Plavix (clopidogrel)

Talk to your doctor before using clopidogrel together with omeprazole. Combining these medications may reduce the effectiveness of clopidogrel in preventing heart attack or stroke. Your doctor or pharmacist may be able to offer suggestions on safer alternatives for stomach acid or ulcer while you are being treated with clopidogrel. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

aspirin clopidogrel

Applies to: aspirin / omeprazole and Plavix (clopidogrel)

Before using aspirin, tell your doctor if you also use clopidogrel. This combination may cause unusual bleeding, severe abdominal pain, weakness, and the appearance of black, tarry stools. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment if you take both medications. You should also avoid any other over-the-counter NSAID products. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

aspirin omeprazole

Applies to: aspirin / omeprazole and aspirin / omeprazole

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

aspirin food

Applies to: aspirin / omeprazole

Ask your doctor before using aspirin together with ethanol. Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

aspirin food

Applies to: aspirin / omeprazole

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer