Drug Interactions between allopurinol and Cardizem LA
This report displays the potential drug interactions for the following 2 drugs:
- allopurinol
- Cardizem LA (diltiazem)
Interactions between your drugs
No interactions were found between allopurinol and Cardizem LA. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
allopurinol
A total of 430 drugs are known to interact with allopurinol.
- Allopurinol is in the following drug classes: antigout agents, antihyperuricemic agents.
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Allopurinol is used to treat the following conditions:
- Calcium Oxalate Calculi with Hyperuricosuria
- Cardiothoracic Surgery (off-label)
- Gout
- High Risk Percutaneous Transluminal Angioplasty (off-label)
- Hyperuricemia Secondary to Chemotherapy
- Leishmaniasis (off-label)
- Mania (off-label)
- Reactive Perforating Collangenosis (off-label)
- Urinary Tract Stones (off-label)
Cardizem LA
A total of 697 drugs are known to interact with Cardizem LA.
- Cardizem la is in the following drug classes: calcium channel blockers, group IV antiarrhythmics.
- Cardizem la is used to treat the following conditions:
Drug and food interactions
allopurinol food
Applies to: allopurinol
Consumer information for this interaction is not currently available.
ADJUST DOSING INTERVAL: The tolerability of allopurinol may be improved by giving it after a meal. Additionally, when the dose is greater than 300 mg, dividing the total daily dose into smaller doses administered more often may be appropriate to help minimize gastrointestinal irritation.
MONITOR: Concomitant use of allopurinol with central nervous system (CNS) depressants, including alcohol, may potentiate adverse effects such as somnolence and sedation.
MANAGEMENT: To improve tolerability, some manufacturers suggest administering allopurinol after a meal. Additionally, if the daily dose is greater than 300 mg, administering allopurinol in divided doses may help reduce gastrointestinal intolerance. Patients should also be counseled to avoid or limit consumption of alcohol and to avoid activities requiring mental alertness such as driving or operating hazardous machinery until they know how the medication affects them.
dilTIAZem food
Applies to: Cardizem LA (diltiazem)
Alcohol can lower your blood pressure and add to the effects of dilTIAZem. You may experience dizziness, lightheadedness, fainting, or a rapid heartbeat if you drink alcohol with dilTIAZem, especially when you first start taking the medication or just after a dose increase. Grapefruit juice may also increase the effects of dilTIAZem in some people by increasing its levels in the blood. You may want to limit alcohol intake and avoid excessive consumption of grapefruit and grapefruit juice during treatment with dilTIAZem. However, if you have been regularly consuming grapefruit or grapefruit juice with dilTIAZem, do not alter the amounts of these products in your diet without first talking to your doctor or other healthcare professional. Contact your doctor if your condition changes or you experience increased side effects of dilTIAZem such as headache, irregular heartbeat, swelling, unexplained weight gain, or chest pain. Orange juice is not expected to interact.
dilTIAZem food
Applies to: Cardizem LA (diltiazem)
Using dilTIAZem together with multivitamin with minerals can decrease the effects of dilTIAZem. Talk with your doctor before using dilTIAZem and multivitamin with minerals together. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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