Drug Interactions between Adhansia XR and Lunesta
This report displays the potential drug interactions for the following 2 drugs:
- Adhansia XR (methylphenidate)
- Lunesta (eszopiclone)
Interactions between your drugs
No interactions were found between Adhansia XR and Lunesta. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Adhansia XR
A total of 198 drugs are known to interact with Adhansia XR.
- Adhansia xr is in the drug class CNS stimulants.
- Adhansia xr is used to treat ADHD.
Lunesta
A total of 369 drugs are known to interact with Lunesta.
- Lunesta is in the drug class miscellaneous anxiolytics, sedatives and hypnotics.
- Lunesta is used to treat Insomnia.
Drug and food interactions
methylphenidate food
Applies to: Adhansia XR (methylphenidate)
GENERALLY AVOID: Alcohol may exacerbate the adverse central nervous system effects of psychoactive drugs, including methylphenidate.
GENERALLY AVOID: Consumption of alcohol while taking certain sustained-release formulations of methylphenidate may cause rapid release of the drug, resulting in increased systemic levels of methylphenidate. In vitro studies have been conducted using Metadate CD 60 mg and Ritalin LA 40 mg capsules, as well as Concerta 18 mg tablet. At an alcohol concentration of 40%, an increase in the release rate of methylphenidate was observed in the first hour for Metadate CD and Ritalin LA, resulting in 84% and 98% of the methylphenidate being released, respectively. In contrast, there was no increased release of methylphenidate in the first hour for Concerta. These results are considered to be representative of the other available strengths of the corresponding product.
MANAGEMENT: Patients treated with methylphenidate should be advised to avoid alcohol or medications that contain alcohol.
References
- (2022) "Product Information. Metadate CD (methylphenidate)." Celltech Pharmaceuticals Inc
- (2002) "Product Information. Concerta (methylphenidate)." Alza
- (2013) "Product Information. Ritalin LA (methylphenidate)." Quality Care Products/Lake Erie Medical
eszopiclone food
Applies to: Lunesta (eszopiclone)
GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of zopiclone and eszopiclone. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.
ADJUST DOSING INTERVAL: Administration of eszopiclone (the S-enantiomer of zopiclone) with or immediately after a high-fat/heavy meal may delay the onset of hypnotic effects. In healthy adults, administration of a 3 mg dose of eszopiclone after a high-fat meal decreased the mean peak plasma drug concentration (Cmax) by 21% and delayed the time to reach peak plasma drug concentration (Tmax) by approximately 1 hour. Theoretically, this interaction should also affect racemic zopiclone.
MANAGEMENT: Patients receiving zopiclone or eszopiclone should be advised to avoid consumption of alcohol. For faster sleep onset, eszopiclone and zopiclone should not be administered with or immediately after a high-fat/heavy meal.
References
- (2004) "Product Information. Lunesta (eszopiclone)." Sepracor Inc
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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