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Histone deacetylase inhibitors

What are Histone deacetylase inhibitors?

Histone deacetylase (HDAC) inhibitors are a group of agents that inhibit the histone deactylase enzymes. During gene expression DNA coils and uncoils around histones. Histone acetylases, acetylate the lysine residues in core histones and histone deactylases remove the acetyl groups from the lysine residues. These actions are important in the regulation of gene expression.

Histone deacetylase inhibitors prevent the deactylation, affect gene expression and causes apoptosis of tumor cells. Histone deacetylase inhibitors are used to treat cutaneous T-cell lymphoma.

List of Histone deacetylase inhibitors:

View by  Brand | Generic
Drug Name Reviews Avg. Ratings
romidepsin systemic (Pro)
1 review
1.0
belinostat systemic (Pro)
0 reviewsAdd rating
panobinostat systemic (Pro)
0 reviewsAdd rating
vorinostat systemic (Pro)
0 reviewsAdd rating
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

See Also

Medical conditions associated with histone deacetylase inhibitors: