Factor Xa inhibitors
What are Factor Xa inhibitors?
Factor Xa inhibitors are a type of anticoagulant that work by selectively and reversibly blocking the activity of clotting factor Xa, preventing clot formation. They affect both factor Xa within the blood and within a preexisting clot. They do not affect platelet aggregation. They are used for the treatment and prevention of deep vein thrombosis and acute pulmonary embolism, and to reduce the risk of stroke and embolism in people with nonvalvular atrial fibrillation.
Factor Xa is generated by both the extrinsic and intrinsic coagulation pathways and is responsible for activating prothrombin to thrombin. Factor Xa inhibitors have predictable anticoagulant effects and do not require routine monitoring, unlike some other anticoagulants.
Apixaban, edoxaban, fondaparinux, and rivaroxaban are all Factor Xa inhibitors.
List of Factor Xa inhibitors:
|Drug Name||View by: Brand | Generic||Reviews||Avg. Ratings|
|fondaparinux systemic (Pro, More...)||5 reviews||8.4|
|rivaroxaban systemic (Pro, More...)||134 reviews||6.3|
|apixaban systemic (Pro, More...)||73 reviews||5.7|
|edoxaban systemic (Pro, More...)||1 review||1.0|
|betrixaban systemic (Pro, More...)||0 reviews||Add rating|
Medical conditions associated with factor Xa inhibitors:
- Atrial Fibrillation
- Deep Vein Thrombosis
- Deep Vein Thrombosis Prophylaxis after Abdominal Surgery
- Deep Vein Thrombosis Prophylaxis after Hip Replacement Surgery
- Deep Vein Thrombosis Prophylaxis after Knee Replacement Surgery
- Deep Vein Thrombosis, Prophylaxis
- Deep Vein Thrombosis, Recurrent Event
- Heart Attack
- Prevention of Thromboembolism in Atrial Fibrillation
- Pulmonary Embolism
- Pulmonary Embolism, Recurrent Event
- Thromboembolic Stroke Prophylaxis
- Venous Thromboembolism