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Sotrovimab Dosage

Medically reviewed by Drugs.com. Last updated on Apr 18, 2022.

Applies to the following strengths: 500 mg/8 mL

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for COVID-19

For investigational use only

500 mg IV as a single dose

Comments:


Use: For the treatment of mild to moderate COVID-19 in patients with positive results of direct SARS-CoV-2 viral testing who are at high risk for progression to severe COVID-19, including hospitalization or death

Usual Pediatric Dose for COVID-19

For investigational use only

12 years or older:


Comments:

Use: For the treatment of mild to moderate COVID-19 in patients with positive results of direct SARS-CoV-2 viral testing who are at high risk for progression to severe COVID-19, including hospitalization or death

Renal Dose Adjustments

Renal dysfunction: No adjustment recommended.

Comments:

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:


Safety and efficacy have not been established in patients younger than 18 years; this drug is not authorized for use in pediatric patients weighing less than 40 kg or those younger than 12 years.

Dialysis

Data not available

Comments:

Other Comments

April 5, 2022: Due to the high frequency of circulating SARS-CoV-2 variants that are nonsusceptible to this drug, sotrovimab is not currently authorized in any US region; therefore, this drug may not be administered for treatment of COVID-19 under the EUA until further notice by the US FDA.

Administration advice:


Storage requirements:

Reconstitution/preparation techniques:

IV compatibility:

General:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.