Sirolimus Topical Dosage

Medically reviewed by Drugs.com. Last updated on Sep 11, 2024.

Usual Adult Dose for Angiofibroma

Usual dose: Apply to the skin of the face affected with angiofibroma twice daily, in the morning and at bedtime.
Maximum dose: 800 mg (2.5 cm)

Comment:
If symptoms do not improve after 12 weeks of treatment, reassess the need for continuation of this drug.

Use: Topical treatment of facial angiofibroma associated with tuberous sclerosis

Usual Pediatric Dose for Angiofibroma

Usual dose: Apply to the skin of the face affected with angiofibroma twice daily in the morning and at bedtime.
Maximum dose: 600 mg (2 cm) for patients 6 to 11 years of age, 800 mg (2.5 cm) for patients 12 to 18 years of age

Comment:
If symptoms do not improve after 12 weeks of treatment, reassess the need for continuation of this drug.

Use: Topical treatment of facial angiofibroma associated with tuberous sclerosis

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:
Contraindicated in patients with a known history of hypersensitivity to sirolimus or any other component.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Bandages, dressings, or wraps should not be used on the skin being treated with sirolimus topical.

• Store at 2C to 8C (36F to 46F). Protect from light.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer