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Kovanaze Dosage

Generic name: TETRACAINE HYDROCHLORIDE 30mg in 1mL, OXYMETAZOLINE HYDROCHLORIDE 0.5mg in 1mL
Dosage form: nasal spray

Medically reviewed by Drugs.com. Last updated on Nov 6, 2024.

Important Dosage and Administration Instructions

  • KOVANAZE is for intranasal use only.
  • Administer ipsilateral (same side) to the maxillary tooth on which the dental procedure will be performed.
  • Wait 10 minutes after administration of KOVANAZE to perform a test drill to confirm that the tooth involved is anesthetized. A patient may not experience the same sensations of numbness or tingling of the lips and cheeks associated with injectable dental anesthetics.

Dosing in Adults (≥ 18 years old)

  • 2 sprays (0.2 mL each) administered 4 to 5 minutes apart in the nostril ipsilateral to the maxillary tooth on which the dental procedure will be performed. Initiate the dental procedure 10 minutes after the second spray.
  • 1 additional spray (0.2 mL) if adequate anesthesia to initiate the dental procedure has not been achieved 10 minutes after the second spray.

Dosing in Children (who weigh 40 kg or more)

  • 2 sprays (0.2 mL each) administered 4 to 5 minutes apart in the nostril ipsilateral to the maxillary tooth on which the dental procedure will be performed. Initiate the dental procedure 10 minutes after the second spray.
Age Group Dose
Adults (≥ 18 years old)
  • 2 sprays (0.2 mL per spray), 4 to 5 minutes apart
  • 1 additional spray (0.2 mL) if adequate anesthesia has not been achieved 10 minutes after the second spray
Children who weigh 40 kg or more
  • 2 sprays (0.2 mL per spray), 4 to 5 minutes apart

More about Kovanaze (oxymetazoline / tetracaine nasal)

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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.