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Fostemsavir Dosage

Medically reviewed by Last updated on Jul 25, 2022.

Applies to the following strengths: 600 mg

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for HIV Infection

600 mg orally twice a day

Use: In combination with other antiretroviral agent(s), for the treatment of HIV-1 infection in heavily treatment-experienced patients with multidrug-resistant HIV-1 infection failing their current antiretroviral regimen due to resistance, intolerance, or safety considerations

Renal Dose Adjustments

Renal dysfunction: No adjustment recommended.

Liver Dose Adjustments

Mild to severe liver dysfunction (Child-Pugh A, B, or C): No adjustment recommended.



  • Previous hypersensitivity to this drug or any of the ingredients
  • Coadministration with strong CYP450 3A inducers (may significantly decrease temsavir [the active moiety of this drug] plasma levels, which may result in loss of virologic response) including, but not limited to, enzalutamide, carbamazepine, phenytoin, rifampin, mitotane, St. John's wort

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Hemodialysis: No adjustment recommended.

Other Comments

Administration advice:

  • Administer with or without food.
  • Swallow tablets whole; do not chew, crush, or split.
  • Consult the manufacturer product information regarding missed doses.

Storage requirements:
  • Store at 20C to 25C (68F to 77F); excursions permitted between 15C and 30C (59F and 86F).

  • The tablets may have a slight vinegar-like odor.

  • Hepatic: Liver chemistries in patients coinfected with HBV and/or HCV

Patient advice:
  • Read the US FDA-approved patient labeling (Patient Information).
  • Notify healthcare provider at once of any signs/symptoms of infection.
  • Consult healthcare provider if symptoms such as dizziness, lightheadedness, abnormal heart rhythm, or loss of consciousness occur.
  • Do not miss or skip doses as resistance may develop.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.