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Dipyridamole Dosage

Medically reviewed by Drugs.com. Last updated on June 5, 2020.

Applies to the following strengths: 25 mg; 50 mg; 75 mg; 5 mg/mL

Usual Adult Dose for Thromboembolic Stroke Prophylaxis

75 to 100 mg orally 4 times a day

Use: Adjunct to warfarin prophylaxis of thromboembolism after cardiac valve replacement

Usual Adult Dose for Thallium Myocardial Imaging

0.142 mg/kg/min IV infusion over 4 minutes

Maximum dose: Unknown; clinical experience suggests not exceeding a total dose of 60 mg

Comments: Thallium-201 should be injected within 5 minutes following the 4-minute infusion of this drug.

Use: Alternative to exercise in thallium myocardial perfusion imaging for evaluation of coronary artery disease (CAD) in patients who cannot exercise adequately.

Usual Pediatric Dose for Thromboembolic Stroke Prophylaxis

12 years or older: 75 to 100 mg orally 4 times a day

Use: Adjunct to warfarin prophylaxis of thromboembolism after cardiac valve replacement

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:
-Hypersensitivity to the active component or any of the ingredients

Safety and efficacy have not been established in patients younger than 18 years (IV); Safety and efficacy have not been established in patients younger than 12 years (oral).

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Storage requirements: IV: Keep covered in carton until time of use and avoid freezing.

Reconstitution/preparation techniques: IV: Dilute in at least a 1:2 ratio with sodium chloride injection 0.45%, sodium chloride injection 0.9%, or dextrose injection 5% for a total volume of approximately 20 to 50 mL.

IV compatibility: Do not mix with other drugs in the same syringe or infusion container.

Monitoring:
-Cardiovascular: IV: ECG tracing (use at least 1 chest lead)
-General: IV: Vital signs (during and for 10 to 15 minutes following IV infusion)

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.