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Cefmetazole Dosage

Applies to the following strengths: 1 g; 2 g; 1 g/50 mL; 2 g/50 mL

Usual Adult Dose for Hysterectomy

Abdominal approach:
1 g IV 30 to 90 minutes before surgery and repeat 8 and 16 hours later.

Vaginal approach:
2 g IV as a single dose 30 to 90 minutes before surgery or 1 g IV 30 to 90 minutes before surgery and repeat 8 and 16 hours later.

Usual Adult Dose for Cesarean Section

2 g IV as a single dose after clamping cord or 1 g IV after clamping cord and repeat 8 and 16 hours later.

Usual Adult Dose for Surgical Prophylaxis

Colorectal surgery:
2 g IV 30 to 90 minutes before surgery and may be repeated 8 and 16 hours later.

Cholecystectomy (high risk):
1 g IV 30 to 90 minutes before surgery and repeat 8 and 16 hours later.

Renal Dose Adjustments

CrCl<10 mL/min: 1 to 2 g IV every 48 hours.

CrCl 10 to 29 mL/min: 1 to 2 g IV every 24 hours.

CrCl 30 to 49 mL/min: 1 to 2 g IV every 16 hours.

CrCl 50 to 90 mL/min: 1 to 2 g IV every 12 hours.

Liver Dose Adjustments

No adjustment recommended

Dialysis

Administer dose after hemodialysis.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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