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Cefmetazole Dosage

Applies to the following strengths: 1 g; 2 g; 1 g/50 mL; 2 g/50 mL

Usual Adult Dose for Hysterectomy

Abdominal approach:
1 g IV 30 to 90 minutes before surgery and repeat 8 and 16 hours later.

Vaginal approach:
2 g IV as a single dose 30 to 90 minutes before surgery or 1 g IV 30 to 90 minutes before surgery and repeat 8 and 16 hours later.

Usual Adult Dose for Cesarean Section

2 g IV as a single dose after clamping cord or 1 g IV after clamping cord and repeat 8 and 16 hours later.

Usual Adult Dose for Surgical Prophylaxis

Colorectal surgery:
2 g IV 30 to 90 minutes before surgery and may be repeated 8 and 16 hours later.

Cholecystectomy (high risk):
1 g IV 30 to 90 minutes before surgery and repeat 8 and 16 hours later.

Renal Dose Adjustments

CrCl<10 mL/min: 1 to 2 g IV every 48 hours.

CrCl 10 to 29 mL/min: 1 to 2 g IV every 24 hours.

CrCl 30 to 49 mL/min: 1 to 2 g IV every 16 hours.

CrCl 50 to 90 mL/min: 1 to 2 g IV every 12 hours.

Liver Dose Adjustments

No adjustment recommended

Dialysis

Administer dose after hemodialysis.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.