Aptivus Dosage

Dosage and Administration Overview

​APTIVUS must be co-administered with ritonavir to exert its therapeutic effect. Failure to correctly co-administer APTIVUS with ritonavir will result in plasma levels of tipranavir that will be insufficient to achieve the desired antiviral effect and will alter some drug interactions.

• ​Children should be assessed for their ability to swallow capsules before prescribing APTIVUS capsules.
• ​APTIVUS co-administered with ritonavir tablets must only be taken with meals.
• ​APTIVUS is supplied as capsules. APTIVUS capsules must be swallowed whole and must not be opened or chewed.
• Due to the need for co-administration of APTIVUS with ritonavir, please refer to the ritonavir prescribing information.

Recommended Dosage in Adults and Pediatric Patients Weighing 36 kg or Higher

​The recommended dosage in adults and pediatric patients weighing 36 kg or higher is 500 mg (two 250 mg capsules) of APTIVUS co-administered with 200 mg of ritonavir, twice daily.