Acetaminophen / Dextromethorphan / Diphenhydramine Dosage

Medically reviewed by Drugs.com. Last updated on Sep 20, 2024.

Usual Adult Dose for Cold Symptoms

Dextromethorphan 10 mg/ diphenhydramine 12.5 mg/ paracetamol 325 mg per 5 mL oral liquid: 10 mL every 4 to 6 hours
Maximum dose: 6 doses per 24 hours

Usual Adult Dose for Influenza

Dextromethorphan 10 mg/ diphenhydramine 12.5 mg/ paracetamol 325 mg per 5 mL oral liquid: 10 mL every 4 to 6 hours
Maximum dose: 6 doses per 24 hours

Usual Pediatric Dose for Cold Symptoms

Dextromethorphan 10 mg/ diphenhydramine 12.5 mg/ paracetamol 325 mg per 5 mL oral liquid:
12 years and older: 10 mL every 4 to 6 hours
Maximum dose: 6 doses per 24 hours

6 to under 12 years: 5 mL every 4 to 6 hours
Maximum dose: 5 doses per 24 hours

Usual Pediatric Dose for Influenza

Dextromethorphan 10 mg/ diphenhydramine 12.5 mg/ paracetamol 325 mg per 5 mL oral liquid:
12 years and older: 10 mL every 4 to 6 hours
Maximum dose: 6 doses per 24 hours

6 to under 12 years: 5 mL every 4 to 6 hours
Maximum dose: 5 doses per 24 hours

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Use with caution.

Precautions

CONTRAINDICATIONS:

• Current use of any other drug containing paracetamol.
• Current use of a monoamine oxidase inhibitor (MAOI) or use within 14 days of stopping a MAOI.
• Current use of any other drug containing diphenhydramine, including topical preparations.

Safety and efficacy have not been established in patients younger than 6 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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