Ekterly Disease Interactions
There are 2 disease interactions with Ekterly (sebetralstat).
Moderate
Sebetralstat (applies to Ekterly) liver dysfunction
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
Avoid the use of sebetralstat in patients with severe liver dysfunction.
References (1)
- (2025) "Product Information. Ekterly (sebetralstat)." Kalvista Pharmaceuticals, Inc.
Moderate
Sebetralstat (applies to Ekterly) renal dysfunction
Moderate Potential Hazard, Moderate plausibility.
The effect of moderate and severe renal dysfunction (eGFR 60 mL/min/1.73 m2 or less) on sebetralstat pharmacokinetics is unknown.
References (1)
- (2025) "Product Information. Ekterly (sebetralstat)." Kalvista Pharmaceuticals, Inc.
Switch to consumer interaction data
Ekterly drug interactions
There are 306 drug interactions with Ekterly (sebetralstat).
Ekterly alcohol/food interactions
There is 1 alcohol/food interaction with Ekterly (sebetralstat).
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More about Ekterly (sebetralstat)
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- FDA approval history
- Drug class: hereditary angioedema agents
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
