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Revumenib Disease Interactions

There are 2 disease interactions with revumenib.

Moderate

Revumenib (applies to revumenib) liver/renal dysfunction

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

Revumenib has not been studied in patients with severe liver or renal impairment.

Moderate

Revumenib (applies to revumenib) prolonged QT interval

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Long QT Syndrome, Congestive Heart Failure, Hypokalemia, Magnesium Imbalance, Arrhythmias

Revumenib can cause QTc interval prolongation. Correct electrolyte imbalances such as hypokalemia and hypomagnesemia, prior to treatment, and perform a baseline ECG. This drug should not be initiated in patients with QTcF greater than 450 msec. Monitor with ECG during treatment (once a week during the first 4 weeks and then monthly). More frequent ECG monitoring may be necessary in patients with congenital long QTc syndrome, congestive heart failure, electrolyte abnormalities, or those taking other medications that can prolong the QTc interval.

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Revumenib drug interactions

There are 555 drug interactions with revumenib.

Revumenib alcohol/food interactions

There is 1 alcohol/food interaction with revumenib.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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