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Oseltamivir Disease Interactions

There are 2 disease interactions with oseltamivir.

Moderate

Oseltamivir (applies to oseltamivir) hepatic impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

The safety and pharmacokinetics of oseltamivir in patients with severe hepatic impairment have not been evaluated. No dose adjustment is required in patients with mild to moderate hepatic impairment.

References

  1. "Product Information. Tamiflu (oseltamivir)." Roche Laboratories PROD (2001):
Moderate

Oseltamivir (applies to oseltamivir) renal impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction

Dose adjustment of oseltamivir treatment is recommended for patients with a serum creatinine clearance between 10 and 30 mL/min. No recommended dosing regimens are available for patients with end-stage disease undergoing routine hemodialysis or continuous peritoneal dialysis treatment.

References

  1. "Product Information. Tamiflu (oseltamivir)." Roche Laboratories PROD (2001):

Oseltamivir drug interactions

There are 8 drug interactions with oseltamivir.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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