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Tamiflu (oseltamivir) Disease Interactions

There are 2 disease interactions with Tamiflu (oseltamivir):

Moderate

Oseltamivir (Includes Tamiflu) ↔ Hepatic Impairment

Moderate Potential Hazard, Moderate plausibility

Applies to: Liver Disease

The safety and pharmacokinetics of oseltamivir in patients with severe hepatic impairment have not been evaluated. No dose adjustment is required in patients with mild to moderate hepatic impairment.

Moderate

Oseltamivir (Includes Tamiflu) ↔ Renal Impairment

Moderate Potential Hazard, Moderate plausibility

Applies to: Renal Dysfunction, hemodialysis

Dose adjustment of oseltamivir treatment is recommended for patients with a serum creatinine clearance between 10 and 30 mL/min. No recommended dosing regimens are available for patients with end-stage disease undergoing routine hemodialysis or continuous peritoneal dialysis treatment.

Tamiflu (oseltamivir) drug Interactions

There are 9 drug interactions with Tamiflu (oseltamivir)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.

Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.

Do not stop taking any medications without consulting your healthcare provider.

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