Nitisinone Disease Interactions
There is 1 disease interaction with nitisinone.
Nitisinone (applies to nitisinone) leukopenia/thrombocytopenia
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Neutropenia
In clinical trials, patients treated with oral formulations of nitisinone and dietary restriction developed transient leukopenia (3%), thrombocytopenia (3%), or both (1.5%). No patients developed infections or bleeding as a result of the episodes of leukopenia and thrombocytopenia. Caution is advised especially in patients with low blood cell counts. Platelet and white blood cell counts should be monitored during therapy with nitisinone.
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Nitisinone drug interactions
There are 243 drug interactions with nitisinone.
Nitisinone alcohol/food interactions
There is 1 alcohol/food interaction with nitisinone.
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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